Evidence map›Paper›PMID 41567386›Full record

ArticleFrontiers in cardiovascular medicine2025

Plasma pharmacokinetics of the combination of potassium chloride extended-release tablets and potassium citrate granules in patients with cardiovascular emergencies.

Xinmei Li, Minghong Qu, Haizhi Li, Te Li

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xinmei LiDepartment of Pharmacy, Fuwai Yunnan Hospital, Chinese Academy of Medical Sciences/Affiliated Cardiovascular Hospital of Kunming Medical University, Kunming, China.
Minghong QuDepartment of Pharmacy, Fuwai Yunnan Hospital, Chinese Academy of Medical Sciences/Affiliated Cardiovascular Hospital of Kunming Medical University, Kunming, China.
Haizhi LiDepartment of Pharmacy, Fuwai Yunnan Hospital, Chinese Academy of Medical Sciences/Affiliated Cardiovascular Hospital of Kunming Medical University, Kunming, China.
Te LiDepartment of Pharmacy, Fuwai Yunnan Hospital, Chinese Academy of Medical Sciences/Affiliated Cardiovascular Hospital of Kunming Medical University, Kunming, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To simulate plasma pharmacokinetics (PK) parameters of combining potassium citrate granules and potassium chloride extended-release tablets using real-world data, guiding optimal dosing and timing for cardiovascular emergency patients. Methods: A retrospective study analyzed PK characteristics in patients receiving both drugs at Fuwai Yunnan Hospital from January 1 to March 31, 2024, using non-compartmental analysis (NCA). Results: Among 330 patients, the Conclusion: PK data fit a 1-compartment model, supporting safe, rational potassium supplementation in cardiovascular emergencies.

Indexed as

cardiovascular diseaseemergency patientnon-compartmental modelplasma potassium parameterspotassium

Identifiers

PMID41567386
PMCPMC12816252

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.