Evidence map›Paper›PMID 41567325›Full record

ArticleFrontiers in nutrition2025

Omega-3 supplementation in addition to prenatal vitamins during pregnancy is associated with lower rates of preterm birth and small for gestational age.

William Yakah, David M Haas, William A Grobman, Lisa D Levine, Uma M Reddy, Robert Silver, Claire-Marie Vacher, Ronald J Wapner, Anna A Penn, Morgan R Firestein

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

William YakahDepartment of Pediatrics, Columbia University Irving Medical Center, New York, NY, United States.
David M HaasDepartment of Obstetrics and Gynecology, School of Medicine, Indiana University, Indianapolis, IN, United States.
William A GrobmanDepartment of Obstetrics and Gynecology, The Ohio State University Wexner Medical Center, Columbus, OH, United States.
Lisa D LevineMaternal Fetal Medicine Division, University of Pennsylvania, Philadelphia, PA, United States.
Uma M ReddyDepartment of Obstetrics & Gynecology, Columbia University Irving Medical Center, New York, NY, United States.
Robert SilverDepartment of Obstetrics and Gynecology, University of Utah, Salt Lake City, UT, United States.
Claire-Marie VacherDepartment of Pediatrics, Columbia University Irving Medical Center, New York, NY, United States.
Ronald J WapnerDepartment of Obstetrics & Gynecology, Columbia University Irving Medical Center, New York, NY, United States.
Anna A Penn *Department of Pediatrics, Columbia University Irving Medical Center, New York, NY, United States.
Morgan R Firestein *Child Health Institute of New Jersey, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Omega-3 fatty acids and prenatal vitamins support fetal growth, but most studies assess omega-3 supplementation without accounting for baseline prenatal vitamin use during pregnancy. In this secondary analysis, we obtained data from the large, prospective Nulliparous Mother-to-be (nuMoM2b) cohort study of 9,461 nulliparous individuals. Participants were enrolled through eight clinical sites across the United States. We compared adverse birth outcomes between those taking additional omega-3 supplements beyond standard prenatal vitamin intake (PNV-OM) vs. prenatal vitamins alone (PNV). PNV-OM intake was associated with significantly lower rates of preterm birth (5.04 vs. 8.41%,

Indexed as

DHAEPAomega - 3 fatty acidspregnancyprenatal vitaminpreterm birthsmall for gestation age (SGA)

Identifiers

PMID41567325
PMCPMC12815722

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.