ArticlePractical laboratory medicine2026
UF-5000 Atyp.C parameter for urinary screening: Impact of detecting atypical and inclusion-bearing cells.
Article in Practical laboratory medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Urine sediment examination is vital for detecting atypical urothelial cells but is highly operator-dependent. The UF-5000 automated urine analyzer quantifies nucleic acid-containing particles. The atypical cell (Atyp.C) parameter reflects increased nucleic acid content and detects atypical urothelial cells and intracytoplasmic inclusion-bearing (ICIB) cells linked to viral infection or inflammation. We assessed the relationship between Atyp.C, atypical cells, and ICIBs and evaluated the parameter's screening performance. Overall, 264 urine sediment samples from 203 patients were analyzed using the UF-5000. Manual microscopy was used to identify atypical and ICIB-positive cells. Atyp.C values were compared between groups using the Mann-Whitney
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