Urinary Neutrophil Mediators as Predictive Biomarkers for Severe Dengue in Adults.

Andrew Teo, Po Ying Chia, Sharlene Ho, Tsin Wen Yeo

Abstract read

In one paragraph

Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andrew TeoDepartment of Respiratory and Infectious Diseaes, Lee Kong Chian School of Medicine,Nanyang Technological University, Singapore, Singapore.ORCID https://orcid.org/0000-0002-4520-2701

Po Ying ChiaDepartment of Respiratory and Infectious Diseaes, Lee Kong Chian School of Medicine,Nanyang Technological University, Singapore, Singapore.ORCID https://orcid.org/0000-0002-8797-9527

Sharlene HoDepartment of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore, Singapore.ORCID https://orcid.org/0000-0002-0607-9579

Tsin Wen YeoDepartment of Respiratory and Infectious Diseaes, Lee Kong Chian School of Medicine,Nanyang Technological University, Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reliable prognostic biomarkers remain an unmet need in dengue. We evaluated urinary neutrophil gelatinase-associated lipocalin and soluble urokinase plasminogen activator receptor for severe dengue prediction in the febrile phase. Urinary neutrophil gelatinase-associated lipocalin and soluble urokinase plasminogen activator receptor demonstrated areas under the receiver operating curve of 0.88 and 0.79, respectively, in discriminating against severe dengue. The noninvasive sampling offers practical advantages as risk stratification tools.

Indexed as

arbovirusneutrophil gelatinase-associated lipocalinneutrophilssevere denguesoluble urokinase plasminogen activator receptor

Identifiers

PMID41567264

DOI10.1093/ofid/ofaf813

PMCPMC12817990

What OpenQuestion holds

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LicenceCC BY

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.