Evidence map›Paper›PMID 41567217›Full record

ArticleFrontiers in immunology2025

Mingyuan Wang, Junjian Sun, Jiang Yu, Jiayun Wang, Chenjing Xu, Jingjing Ma, Hongjie Zhang

Abstract read
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mingyuan WangDepartment of Gastroenterology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Junjian SunDepartment of Gastroenterology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Jiang YuDepartment of Gastroenterology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Jiayun WangDepartment of Gastroenterology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Chenjing XuDepartment of Gastroenterology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
Jingjing MaDepartment of Gastroenterology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Hongjie ZhangDepartment of Gastroenterology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Crohn's disease (CD) is a chronic relapsing inflammatory bowel disease characterized by persistent mucosal inflammation and immune dysregulation. While alterations in gut microbial composition are known to contribute to CD pathogenesis, the precise mechanisms linking specific microbial species to immune dysfunction remain unclear. Here, we identify Methods: Fecal and colonic mucosal samples from CD patients and healthy controls were analyzed by 16S rRNA sequencing. A TNBS-induced colitis model with adoptive DC transfer, was used to evaluate the impact of Results: Conclusions: This study demonstrates that

Indexed as

CD40 AntigensCrohn DiseaseDendritic CellsFusobacterium InfectionsFusobacterium nucleatumTh17 CellsT-Lymphocytes, RegulatoryAnimalsColitisDisease Models, AnimalFemaleHumansInflammationIntestinal MucosaMaleMiceCD40 AntigensCD40Crohn’s diseasedendritic cellsFusobacterium nucleatumTh17/Treg balance

Identifiers

PMID41567217
PMCPMC12815848

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.