ArticleJournal of cosmetic dermatology2026
Impact of Fatigue on the Skin: Pilot Study on "996" Work-Life Pattern in China and the Influence of Their Lifestyle on the Skin.
Article in Journal of cosmetic dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Impact of Fatigue on the Skin: Pilot Study on "996" Work-Life Pattern in China and the Influence of Their Lifestyle on the Skin.Journal of cosmetic dermatology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundModern living encouraged longer working hours and an increased sense of fatigue. In China, a rising trend called "996", meaning working from 9 a.m. to 9 p.m., 6 days per week in succession, has raised concerns about the impact of fatigue on health, specifically on skin aging.
methodsA one-week, single center, self-controlled clinical study was conducted to evaluate the impact of fatigue on skin phenotypes, through the enrollment of 31 Chinese women with a 996 work-life pattern based on Life Style questionnaires and Chalder fatigue scale. Clinical grading and instrumental measurements were conducted before the working week, after 1, 3, and 5 working days.
resultsThe fatigue score of the participants accumulated during the working week. From clinical grading, periocular fine lines, fine lines of the cheeks, and forehead wrinkles were significantly worsened in the working week compared to the weekend. Skin elasticity parameters R0, R5, and R7 were also significantly worse compared to the weekend. Significantly increased porphyrin, yellowness, and decrease of redness of skin during working times were also observed. Additionally, the clinical evaluations were well recorded with self-perceptions from the questionnaire.
conclusionFatigue is an inescapable stressor in modern life that impacts skin's health and appearance by accelerating signs of aging, altering skin color, and increasing risk of acne. This is a pilot study analyzing the population with intensive work-life patterns, serving as a reference to comprehensively assess the impact of modern living on skin.
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