Evidence map›Paper›PMID 41566455›Full record

ArticleBMC women's health2026

Prospective cohort study: vascular clamping of uterine artery combined with sacral ligament plication in complex hysterectomy.

Junjie Xu, Shisi Xiong, Rui Gu, Rong Yuan, Danyan Feng, Shanshan Cong, Shaojie Zhao, Liping Jiang

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Article in BMC women's health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Junjie Xu *Wuxi Maternity and Child Health Care Hospital, Wuxi Medical Center of Nanjing Medical University, Wuxi, 214000, China.
Shisi Xiong *Wuxi Maternity and Child Health Care Hospital, Wuxi School of Medicine, Jiangnan University, Wuxi, 214002, China.
Rui GuDepartment of Gynaecology, Wuxi Maternity and Child Health Care Hospital, Affiliated Women's Hospital of Jiangnan University, Wuxi, 214000, China.
Rong YuanDepartment of Gynaecology, Wuxi Maternity and Child Health Care Hospital, Affiliated Women's Hospital of Jiangnan University, Wuxi, 214000, China.
Danyan FengDepartment of Gynaecology, Wuxi Maternity and Child Health Care Hospital, Affiliated Women's Hospital of Jiangnan University, Wuxi, 214000, China.
Shanshan CongDepartment of Gynaecology, Wuxi Maternity and Child Health Care Hospital, Affiliated Women's Hospital of Jiangnan University, Wuxi, 214000, China.
Shaojie ZhaoDepartment of Gynaecology, Wuxi Maternity and Child Health Care Hospital, Affiliated Women's Hospital of Jiangnan University, Wuxi, 214000, China.
Liping JiangWuxi Maternity and Child Health Care Hospital, Wuxi Medical Center of Nanjing Medical University, Wuxi, 214000, China. fckjlp1982@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the clinical efficacy of the combined technique involving Hem-o-lok clip closure of the uterine artery trunk and uterosacral ligament plication in laparoscopic complex hysterectomy.

methodsA prospective study included 100 patients undergoing laparoscopic complex hysterectomy at our hospital from January 2021 to June 2022. Patients were divided into the conventional group (n = 50) and the combined group (n = 50) based on surgical techniques. The conventional group underwent standard electrocoagulation closure of the ascending uterine artery branch at the cervical isthmus level and simple vaginal cuff suture, while the combined group utilized Hem-o-lok vascular clips for early uterine artery trunk closure and additional uterosacral ligament plication fixation to the vaginal cuff. Intraoperative blood loss, operative time, postoperative recovery indicators, and 3-year follow-up outcomes-including pelvic floor function (POP-Q staging, PFDI-20 score) and sexual quality of life (FSFI score)-were compared.

resultsCompared with the conventional group, the combined group demonstrated significantly reduced intraoperative blood loss (68.7 ± 15.2 vs.95.2 ± 18.4mL, P < 0.001) higher surgical field visibility scores (4.8 ± 0.3 vs. 3.1 ± 0.7, P < 0.01), faster postoperative recovery, and lower hospitalization costs. At 3-year follow-up, the combined group exhibited lower rates of POP-Q stage ≥Ⅱ (6% vs. 24%, P < 0.01), longer vaginal length (8.1 ± 0.8 vs. 7.0 ± 1.2 cm, P < 0.01), lower PFDI-20 scores (18.5 ± 4.5 vs. 35.7 ± 7.8, P < 0.01), and higher FSFI scores (25.2 ± 2.6 vs. 20.3 ± 4.1, P < 0.01).

conclusionT The combined technique of uterine artery trunk closure with Hem-o-lok clips and uterosacral ligament plication significantly improved surgical efficiency without increasing major complications. Furthermore, in this prospective cohort, it was associated with a shorter operative time, less blood loss, and better pelvic floor and sexual function metrics at the 3-year follow-up compared to the conventional technique.

Indexed as

HysterectomyLaparoscopyLigamentsUterine ArteryAdultBlood Loss, SurgicalFemaleHumansMiddle AgedOperative TimeProspective StudiesQuality of LifeSacrumTreatment OutcomeUterusComplex hysterectomyPelvic floor functionSacral ligament plicationUterine arteryVascular clip (Hem-o-lok)

Identifiers

PMID41566455
PMCPMC12910999

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.