Evidence map›Paper›PMID 41566408›Full record

ArticleBMC psychology2026

Sleep characteristics and risk factors in patients of insomnia comorbid with anxiety.

Cong Wang, Sangyi Lin, Wenlin Xu, Xinghong Bing, Chaojun Fang, Yijia Wan, Shuo Jiang, Na Zhao, Chen Xie

Abstract read
In one paragraph

Article in BMC psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Anxiety disorders: a cross-sectional study of clinical and biological associations.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cong Wang *Department of Acupuncture and Moxibustion, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, 310006, China.
Sangyi Lin *Department of Rehabilitation, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, 310006, China.
Wenlin XuDepartment of Massage, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, 310006, China.
Xinghong BingShanghai Jiading District Hospital of Traditional Chinese Medicine, Shanghai, 201899, China.
Chaojun FangShanghai Research Institute of Acupuncture and Meridian, Shanghai, 200030, China.
Yijia WanDepartment of Acupuncture and Moxibustion, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, 310006, China.
Shuo JiangDepartment of Acupuncture and Moxibustion, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, 310006, China.
Na ZhaoYueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, China. zhaoziqing1988@126.com.
Chen XieShanghai Research Institute of Acupuncture and Meridian, Shanghai, 200030, China. xiechen2000@163.com.

Funding

National Natural Science Foundation of China 81804200National Natural Science Foundation of China 82405536
6 · The paper itself

Abstract

backgroundInsomnia is a common sleep disturbance that often co-occurs with anxiety. While insomnia is a known risk factor for anxiety, anxiety can also exacerbate insomnia. This hypothesis-driven study aimed to: (1) test whether patients of insomnia comorbid with anxiety exhibit greater subjective-objective sleep discrepancy than those with insomnia alone; and (2) identify risk factors for comorbidity and predictors of anxiety severity.

methodsA total of 221 patients with insomnia were recruited and divided into an anxiety group (n = 163) and a non-anxiety group (n = 58) according to the Beck Anxiety Inventory (BAI) ≥ 10 points or < 10 points. Subjective sleep and emotional states were assessed using the Pittsburgh Sleep Quality Index (PSQI), Insomnia Severity Index (ISI), Beck Depression Inventory (BDI), and BAI. Objective sleep parameters (e.g., total sleep time, sleep efficiency) were monitored via 7-day actigraphy (ACT). Differences and correlations among subjective scales and objective indicators were analyzed using Logistic regression and Spearman correlation analyses to identify sleep characteristics and risk factors for insomnia comorbid with anxiety.

resultsThe anxiety group showed significantly higher PSQI, ISI, BDI, and BAI scores compared to the non-anxiety group (all P < 0.001). Act data indicated that the anxiety group spent more time in bed (P = 0.017), but no significant differences were observed in total sleep time, sleep efficiency, sleep onset latency, or wake time after sleep onset (P > 0.05). The anxiety group also exhibited more severe sleep disturbances and daytime dysfunction in PSQI subitems (P < 0.05). Spearman correlation analysis revealed positive correlations between BAI grade and PSQI, ISI, and BDI grades (all P < 0.05). Both univariate and multivariate binomial logistic regression analyses indicated that a disease duration of 36–120 months significantly increased the risk of insomnia comorbid with anxiety (P < 0.05). Ordinal logistic regression further identified sleep efficiency (P = 0.008), sleep disturbances (P<0.001) and daytime dysfunction (P = 0.043) as significant positive predictors of anxiety severity.

conclusionsPatients of insomnia comorbid with anxiety report poorer subjective sleep quality, more depressive symptoms, and longer time in bed. PSQI, ISI, and BDI scores are associated with the development of insomnia comorbid with anxiety. Sleep efficiency, sleep disturbances, and daytime dysfunction are significant factors influencing anxiety severity. Disease duration is a core risk factor and should be addressed clinically through early intervention.

Indexed as

AnxietySleepSleep Initiation and Maintenance DisordersSleep QualityActigraphyAdultComorbidityFemaleHumansMaleMiddle AgedRisk FactorsSeverity of Illness IndexSleep DurationAnxietyInsomniaRisk factorsSleep characteristics

Identifiers

PMID41566408
PMCPMC12911087

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.