Evidence map›Paper›PMID 41566234›Full record

Observational studyBMC gastroenterology2026

Long-term clinical course, treatment patterns, and prognosis in pediatric-onset vs. adult-onset IBD: a multicenter retrospective cohort study in Korea.

Yong Eun Park, Su Bum Park, Sang-Bum Kang, Yehyun Park, Dae Sung Kim, Soo-Young Na, Won Moon, IBD Research Group of the Korean Association for the Study of Intestinal Diseases (KASID)

Abstract readComparative StudyMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMC gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yong Eun ParkDivision of Gastroenterology, Department of Internal Medicine, Inje University School of Medicine, Haeundae Paik Hospital, Busan, Republic of Korea.
Su Bum ParkDepartment of Internal Medicine, Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, 50612, Republic of Korea. psubumi@pusan.ac.kr.
Sang-Bum KangDivision of Gastroenterology, Department of Internal Medicine, Daejeon St. Mary's Hospital, College of Medicine, the Catholic University of Korea, Daejeon, Korea.
Yehyun ParkDivision of Gastroenterology, Department of Internal Medicine, Ewha Womans University Seoul Hospital, Seoul, Korea.
Dae Sung KimDepartment of Internal Medicine, Konyang University College of Medicine, Daejeon, Republic of Korea.
Soo-Young NaDivision of Gastroenterology, Department of Internal Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Won MoonDepartment of Internal Medicine, Kosin University College of Medicine, Busan, Republic of Korea.
IBD Research Group of the Korean Association for the Study of Intestinal Diseases (KASID)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to compare the long-term clinical characteristics, treatment patterns, and prognosis of inflammatory bowel disease (IBD) in patients diagnosed before and after 18 years of age.

methodsA retrospective study was conducted using data from 384 patients with IBD with a disease duration exceeding 10 years across five hospitals. Baseline characteristics, disease status, and treatment patterns were analyzed at diagnosis, 5 years, 10 years, and present.

resultsOf the 384 patients, 84 (21.9%) and 300 (78.1%) were diagnosed before and at or older than the age of 18 years, respectively. Patients diagnosed before 18 years of age more frequently presented with Crohn’s disease (CD) (83.3% vs. 40.0%), whereas ulcerative colitis (UC) was predominant in those diagnosed later (16.7% vs. 60.0%). Younger patients had a significantly higher prevalence of abdominal pain (64.3% vs. 48.7%), malnutrition/weight loss (21.4% vs. 10.7%), and anal fistulas/abscesses (26.2% vs. 5.7%) at the time of diagnosis. Younger patients had more pancolitis-type UC (50% vs. 32.2%) and more perianal diseases in the CD group (51.4% vs. 20.8%). Younger patients initially exhibited higher rates of steroid usage, with a gradual shift towards biologics, such as infliximab. Multivariable Cox regression identified discontinuation of biologic therapy during follow-up as a significant risk factor for disease recurrence.

conclusionOur findings suggest that the age at IBD onset significantly is associated with disease progression and treatment outcomes, underscoring the need for age-tailored management strategies in long-term IBD care.

Indexed as

Colitis, UlcerativeCrohn DiseaseInflammatory Bowel DiseasesAdolescentAdultAge of OnsetChildDisease ProgressionFemaleHumansMaleMiddle AgedPrognosisRepublic of KoreaRetrospective StudiesYoung AdultInflammatory bowel diseaseLong-termPediatricsRisk factors

Identifiers

PMID41566234
PMCPMC12905910

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.