Evidence map›Paper›PMID 41565907›Full record

ArticleScientific reports2026

Prophage-encoded RexAB-type phage defense system in Pseudomonas putida.

Sirli Rosendahl, Anu Kängsep, Andres Ainelo, Anita Lipu, Hedvig Tamman, Rita Hõrak

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sirli RosendahlInstitute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia.
Anu KängsepInstitute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia.
Andres AineloInstitute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia.
Anita LipuInstitute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia.
Hedvig TammanInstitute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia.
Rita HõrakInstitute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia. rita.horak@ut.ee.

Funding

Eesti Teadusagentuur PRG1431Eesti Teadusagentuur STP39European Research Council 101116205
6 · The paper itself

Abstract

Temperate bacteriophages in their prophage form are abundant residents in bacterial genomes. As the fitness of a prophage depends on the welfare of its host, prophages often encode genes that enhance their host's fitness, thereby also contributing to their own survival. One such strategy for mutual survival is to protect the host from superinfection by other phages. We recently showed that four cryptic prophages contribute to the phage resistance of Pseudomonas putida, a metabolically versatile and industrially promising model bacterium. Here, we show that prophages 1, 2, and 3 exhibit anti-phage activity against specific phages in our CEPEST collection. Focusing on P1-mediated phage defense, we uncover that P1 genes PP_5643 and PP_5644 encode a two-component RexAB-type phage immunity system. The RexA

Indexed as

ProphagesPseudomonas putidaViral ProteinsBacterial ProteinsBacterial ProteinsViral ProteinsCEPEST collectionPhage defense systemProphagePseudomonas putidaRexAB

Identifiers

PMID41565907
PMCPMC12894663

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.