ArticleNature2026
LetA defines a structurally distinct transporter family.
Abstract read
In one paragraph
Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Interactions of outer membrane lipoproteins Pseudomonas aeruginosa PA3214 and Escherichia coli PqiC with their MCE protein binding partners, PA3213 and PqiB.The Journal of biological chemistry · 2026Article
- Bacterial lipids traverse the hydrophobic groove of TamB.Biophysical journal · 2026Article
- Identification of theBiology · 2026Article
- Integration of Membrane Proteins into the Outer Membrane of Diderm Bacteria by the BAM Complex.Chemical reviews · 2026Review
Corrections and comments
- Update of
Authors and funding
18 authors.
Cristina C SantarossaDepartment of Biology, Johns Hopkins University, Baltimore, MD, USA.
Yupeng LiTheoretical and Computational Biophysics Group, NIH Resource for Macromolecular Modeling and Visualization, Department of Biochemistry, and Center for Biophysics and Quantitative Biology, Beckman Institute for Advanced Science and Technology, University of Illinois Urbana-Champaign, Urbana, IL, USA.ORCID 0000-0003-4057-532X
Sara YousefDepartment of Biology, Johns Hopkins University, Baltimore, MD, USA.
Hale S HasdemirTheoretical and Computational Biophysics Group, NIH Resource for Macromolecular Modeling and Visualization, Department of Biochemistry, and Center for Biophysics and Quantitative Biology, Beckman Institute for Advanced Science and Technology, University of Illinois Urbana-Champaign, Urbana, IL, USA.ORCID 0000-0001-9191-6062
Carlos C RodriguezTheoretical and Computational Biophysics Group, NIH Resource for Macromolecular Modeling and Visualization, Department of Biochemistry, and Center for Biophysics and Quantitative Biology, Beckman Institute for Advanced Science and Technology, University of Illinois Urbana-Champaign, Urbana, IL, USA.
Max A B HaaseDepartment of Mechanistic Cell Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany.ORCID 0000-0002-8962-0446
Minkyung BaekDepartment of Biological Sciences, Seoul National University, Seoul, Republic of Korea.ORCID 0000-0003-3414-9404
Nicolas CoudrayDepartment of Biology, Johns Hopkins University, Baltimore, MD, USA.
John G PavekDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, USA.
Kimber N FockeDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, USA.
Annika L SilverbergDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, USA.
Carmelita BautistaCold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
Johannes T-H YehCold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
Michael T MartyDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, USA.ORCID 0000-0001-8115-1772
David BakerInstitute for Protein Design, University of Washington, Seattle, WA, USA.ORCID 0000-0001-7896-6217
Emad TajkhorshidTheoretical and Computational Biophysics Group, NIH Resource for Macromolecular Modeling and Visualization, Department of Biochemistry, and Center for Biophysics and Quantitative Biology, Beckman Institute for Advanced Science and Technology, University of Illinois Urbana-Champaign, Urbana, IL, USA.ORCID 0000-0001-8434-1010
Damian C EkiertDepartment of Biology, Johns Hopkins University, Baltimore, MD, USA. damian.ekiert@be-labs.org.ORCID 0000-0002-2570-0404
Gira BhabhaDepartment of Biology, Johns Hopkins University, Baltimore, MD, USA. gira.bhabha@be-labs.org.ORCID 0000-0003-0624-6178
Funding
Single-Cell Biology Shared ResourceP30CA045508 · NCI · COLD SPRING HARBOR LABORATORY · PI David A Tuveson · 1987 to 2026
$118.9MVaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MARK Reid PHILIPS · 1985 to 2026
$83.1MNCCAT: National Center for CryoEM Access and Training- Supplement for Windows 10 and FFIU24GM129539 · NIGMS · NEW YORK STRUCTURAL BIOLOGY CENTER · PI DE MARCO, ALEX, KIEFT, JEFFREY S · 2018 to 2023
$53.9MPacific Northwest Center for Cryo-EM: Equipment SupplementR24GM154185 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI James E Evans, CLAUDIA SUSANA LOPEZ · 2024 to 2026
$21.5MNCCAT: National Center for CryoEM Access and TrainingR24GM154192 · NIGMS · NEW YORK STRUCTURAL BIOLOGY CENTER · PI EDWARD T ENG, Jeffrey S Kieft · 2024 to 2026
$21.0MResource for Macromolecular Modeling and VisualizationR24GM145965 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Emad Tajkhorshid · 2022 to 2026
$6.2MUnravelling lipid trafficking for the bacterial outer membraneR35GM128777 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Damian Ekiert · 2018 to 2026
$4.1MTransport Cycle and Inhibition of Human Na+-dicarboxylate Cotransporter NaDC3R01NS108151 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DANENG WANG · 2018 to 2026
$4.1MUnravelling Membrane Protein-Lipid Interactions using Nanodiscs and Mass SpectrometryR35GM128624 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI Michael T Marty · 2018 to 2026
$3.6MMolecular mechanism of Na+ -coupled HCO3- transporters: transport of CO3= and CO2R01DK128315 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI BORON, WALTER F, TAJKHORSHID, EMAD · 2021 to 2024
$2.7MStructure and function of the LetA lipid transport family across bacteria and eukaryotesK99GM157496 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI SANTAROSSA, CRISTINA · 2024 to 2025
$250kNCI NIH HHS P30 CA016087NCI NIH HHS P30 CA045508NIDDK NIH HHS R01 DK128315NIGMS NIH HHS K99 GM157496NIGMS NIH HHS R24 GM145965NIGMS NIH HHS R24 GM154185NIGMS NIH HHS R24 GM154192NIGMS NIH HHS R35 GM128624NIGMS NIH HHS R35 GM128777NIGMS NIH HHS U24 GM129539NINDS NIH HHS R01 NS108151
Abstract
Membrane transport proteins translocate diverse cargos, ranging from small sugars to entire proteins, across cellular membranes
Indexed as
Escherichia coliEscherichia coli ProteinsMembrane Transport ProteinsBacterial ProteinsBiological TransportCell MembraneMembrane ProteinsModels, MolecularMolecular Dynamics SimulationProtein DomainsBacterial ProteinsCcdA protein, BacteriaEscherichia coli ProteinsMembrane ProteinsMembrane Transport ProteinsYebT protein, E coli
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.