Evidence map›Paper›PMID 41565822›Full record

ArticleNature2026

Biological insights into schizophrenia from ancestrally diverse populations.

Tim B Bigdeli, Chris Chatzinakos, Jaroslav Bendl, Peter B Barr, Sanan Venkatesh, Bryan R Gorman, Tereza Clarence, Giulio Genovese, Conrad O Iyegbe, Roseann E Peterson and 38 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Reprogramming of neuronal genome function and phenotype by astrocytes.bioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

48 authors.

Tim B BigdeliVA New York Harbor Healthcare System, New York, NY, USA. tim.bigdeli@va.gov.ORCID 0000-0003-2215-5946
Chris Chatzinakos *Institute for Genomics in Health (IGH), SUNY Downstate Health Sciences University, New York, NY, USA.
Jaroslav Bendl *Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0001-9989-2720
Peter B Barr *VA New York Harbor Healthcare System, New York, NY, USA.ORCID 0000-0001-9321-657X
Sanan VenkateshCenter for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Bryan R GormanMassachusetts Area Veterans Epidemiology Research and Information Center (MAVERIC), Boston, MA, USA.ORCID 0000-0002-4239-4672
Tereza ClarenceCenter for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Giulio GenoveseStanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID 0000-0003-3066-5575
Conrad O IyegbeDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Roseann E PetersonVA New York Harbor Healthcare System, New York, NY, USA.ORCID 0000-0001-6402-849X
Sergios-Orestis KolokotronisDepartment of Psychiatry and Behavioral Sciences, SUNY Downstate Health Sciences University, New York, NY, USA.ORCID 0000-0003-3309-8465
David BursteinCenter for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Jacquelyn L MeyersInstitute for Genomics in Health (IGH), SUNY Downstate Health Sciences University, New York, NY, USA.
Yuli LiClinical Epidemiology Research Center (CERC), VA Connecticut Healthcare System, West Haven, CT, USA.
Sundar NatarajanVA New York Harbor Healthcare System, New York, NY, USA.
Michael O FrancisMassachusetts Area Veterans Epidemiology Research and Information Center (MAVERIC), Boston, MA, USA.ORCID 0000-0002-1320-7161
Nallakkandi RajeevanClinical Epidemiology Research Center (CERC), VA Connecticut Healthcare System, West Haven, CT, USA.
Kei-Hoi CheungClinical Epidemiology Research Center (CERC), VA Connecticut Healthcare System, West Haven, CT, USA.
Project Among African-Americans to Explore Risks for Schizophrenia (PAARTNERS)
Consortium on the Genomics of Schizophrenia (COGS)
Genomic Psychiatry Cohort (GPC) Investigators
Lynn E DeLisiDepartment of Psychiatry, Cambridge Health Alliance, Cambridge, MA, USA.
Thomas R KostenMichael E. DeBakey VA Medical Center, Houston, TX, USA.ORCID 0000-0003-1505-555X
Hongyu ZhaoClinical Epidemiology Research Center (CERC), VA Connecticut Healthcare System, West Haven, CT, USA.ORCID 0000-0003-1195-9607
Eric AchtyesWestern Michigan University Homer Stryker M.D. School of Medicine, Kalamazoo, MI, USA.ORCID 0000-0001-8939-1535
Peter F BuckleyUniversity of Tennessee Health Science Center in Memphis, Memphis, TN, USA.
Dolores MalaspinaDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Douglas LehrerDepartment of Psychiatry, Wright State University, Dayton, OH, USA.
Mark H RapaportHuntsman Mental Health Institute, Department of Psychiatry, University of Utah, Salt Lake City, UT, USA.
David L BraffDepartment of Psychiatry, University of California, San Diego, San Diego, CA, USA.
Michele T PatoDepartment of Psychiatry, Robert Wood Johnson Medical School, New Brunswick, NJ, USA.
Ayman H FanousDepartment of Psychiatry, University of Arizona College of Medicine-Phoenix, Phoenix, AZ, USA.
Carlos N PatoDepartment of Psychiatry, Robert Wood Johnson Medical School, New Brunswick, NJ, USA.
PsychAD Consortium
VA Cooperative Studies Program (CSP) #572
VA Million Veteran Program (MVP)
Grant D HuangOffice of Research and Development, Veterans Health Administration, Washington, DC, USA.
Sumitra MuralidharOffice of Research and Development, Veterans Health Administration, Washington, DC, USA.ORCID 0000-0001-8417-9068
J Michael GazianoMassachusetts Area Veterans Epidemiology Research and Information Center (MAVERIC), Boston, MA, USA.
Saiju PyarajanMassachusetts Area Veterans Epidemiology Research and Information Center (MAVERIC), Boston, MA, USA.ORCID 0000-0002-9047-3762
Kiran GirdharCenter for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-5622-042X
Donghoon LeeCenter for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0003-0453-6059
Gabriel E HoffmanCenter for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-0957-0224
Mihaela AslanClinical Epidemiology Research Center (CERC), VA Connecticut Healthcare System, West Haven, CT, USA.
John F FullardCenter for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0001-9874-2907
Georgios VoloudakisCenter for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-5729-632X
Philip D HarveyBruce W. Carter Miami Veterans Affairs (VA) Medical Center, Miami, FL, USA.
Panos RoussosCenter for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY, USA. panagiotis.roussos@va.gov.ORCID 0000-0002-4640-6239

Funding

Research Center in Minority Institutions (RCMI) at City CollegeU54MD017979 · NIMHD · CITY COLLEGE OF NEW YORK · PI M. Felice Marina GHILARDI · 2024 to 2026
$15.9M
Understanding the molecular mechanisms that contribute to neuropsychiatric symptoms in Alzheimer DiseaseR01AG067025 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI FINKBEINER, STEVEN M, HAROUTUNIAN, VAHRAM · 2019 to 2023
$11.8M
Identifying genetically driven gene dysregulation in Alzheimer's disease and related dementias using statistical data integrationR01AG078657 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Georgios Voloudakis · 2023 to 2026
$2.7M
Characterizing and targeting subphenotypes of schizophrenia and bipolar disorder via individually imputed tissue and cell-type specific transcriptomesK08MH122911 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI VOLOUDAKIS, GEORGIOS · 2020 to 2023
$770k
NIA NIH HHS R01 AG067025NIA NIH HHS R01 AG078657NIMHD NIH HHS U54 MD017979NIMH NIH HHS K08 MH122911
6 · The paper itself

Abstract

Schizophrenia and related psychoses occur in all human populations, with the highest rates of diagnosis among Black individuals and those of mainly African ancestry

Indexed as

Genetic Predisposition to DiseaseSchizophreniaBlack or African AmericanBlack PeopleElectronic Health RecordsFemaleGenome-Wide Association StudyHumansMaleMultifactorial InheritanceTranscriptomeUnited StatesVeteransWhiteWhite People

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.