ArticleEuropean radiology2026
Clinical outcomes after TIPS: comparison of patients with a history of partial splenic embolization vs splenectomy in cirrhosis.
Article in European radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
objectivesTo compare clinical outcomes of transjugular intrahepatic portosystemic shunt (TIPS) in cirrhotic patients with a history of partial splenic embolization (PSE) vs splenectomy, focusing on shunt patency, overt hepatic encephalopathy (OHE), rebleeding, and survival. MATERIAL AND
methodsThis retrospective study included 240 cirrhotic patients undergoing TIPS (TIPS + PSE: n = 126; TIPS + splenectomy: n = 114). After propensity score matching, 88 patients per group were analyzed. The primary endpoint was shunt dysfunction; secondary endpoints included OHE, rebleeding, and survival.
resultsTIPS + PSE group had lower rates of shunt dysfunction (10.2% vs 30.7%, p < 0.001) and OHE (17.1% vs 39.8%, p < 0.001) than TIPS+splenectomy. No differences were found in rebleeding or survival (p > 0.05). Cox regression showed the treatment group (PSE vs splenectomy) as an independent predictor of shunt dysfunction (HR = 3.24, 95% CI: 1.56-6.91, p = 0.002) and OHE (HR = 1.96, 95% CI: 1.03-3.74, p = 0.042). Portal vein thrombosis was identified as an independent predictor of shunt dysfunction (HR = 2.47, 95% CI: 1.16-5.27, p = 0.019). Age (HR = 1.04, 95% CI: 1.00-1.08, p = 0.046) and Model for end-stage liver disease score (HR = 1.20, 95% CI: 1.02-1.41, p = 0.027) were independent predictors of mortality.
conclusionsAmong patients undergoing TIPS, those with prior PSE had a more favorable outcome regarding shunt dysfunction and OHE than those with prior splenectomy, with comparable rebleeding and survival. These findings support prioritizing PSE over splenectomy for patients who may later require TIPS. KEY POINTS: Question The influence of prior splenic intervention on outcomes after TIPS in cirrhotic patients with portal hypertension remains uncertain, particularly regarding the comparative effects of PSE vs splenectomy. Finding Among patients undergoing TIPS, those with prior PSE had a more favorable outcome regarding shunt dysfunction and OHE than those with prior splenectomy, with comparable rebleeding and survival. Clinical relevance TIPS after PSE offers better outcomes in reducing shunt dysfunction and overt OHE in cirrhotic patients with portal hypertension, supporting prioritizing PSE over splenectomy for patients who may later require TIPS.
Indexed as
Identifiers
41565795What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.