ArticleBMJ open2026
Effectiveness of cognitive behavioural therapy-based intervention on depression and anxiety in high-risk pregnant women: a systematic review protocol.
Article in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionHigh-risk pregnant women with physical or obstetric complications may develop depression and anxiety disorders that may worsen depending on the consequences of treatment and management during pregnancy. Therefore, their psychological well-being requires particular attention under these conditions. Consideration of specific and effective interventions for depression and anxiety would help improve the psychological outcomes of these women. This review aims to evaluate the effectiveness of cognitive behavioural therapy-based interventions for depression and anxiety in high-risk pregnant women. METHODS AND ANALYSIS: This systematic review will follow the Joanna Briggs Institute (JBI) methodology for systematic reviews of effectiveness. The searches will be conducted in English in the following databases: MEDLINE, CINAHL, Web of Science, PsycINFO and Cochrane Central Register of Controlled Trials. Additionally, the Ichushi Web will be searched in English and Japanese. Sources of unpublished studies will be searched using ClinicalTrials.gov and the UMIN Clinical Trials Registry. Grey literature will be searched using DANS Data Stations. The JBI guidelines will be used for screening studies, study selection, critical appraisal, data extraction and integration. The Grading of Recommendations, Assessment, Development and Evaluation approach will be used to evaluate the certainty of the findings by two independent reviewers. If possible, statistical meta-analyses will be pooled. Additionally, the statistical heterogeneity will be assessed. Subgroup analysis will be performed according to participant and intervention characteristics. Funnel plots, Egger, Begg and Harbord tests will be used to detect publication bias, if necessary. ETHICS AND DISSEMINATION: This systematic review does not require an ethics approval, as the data will be evaluated from previously published studies. The findings will be disseminated through publication in an international peer-reviewed journal and presented at research conferences. PROSPERO REGISTRATION NUMBER: CRD42024522468.
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