Evidence map›Paper›PMID 41565239›Full record

ArticleAsia Pacific journal of clinical nutrition2026

Vitamin B12 and D status in long-term vegetarians: Impact of diet duration and subtypes in Beijing, China.

Yun Wang, Xiaowei Xin, Hui Zhang, Ying Jia, Zhiheng Liu, Zhijian Xu, Yehua Gan, Suyun Li

Abstract read
In one paragraph

Article in Asia Pacific journal of clinical nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yun WangBeijing Zhongguancun Hospital, Beijing, China.
Xiaowei XinCancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Hui ZhangCancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Ying JiaCancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Zhiheng LiuBeijing Rike Healthcare Technology Co., Ltd, Beijing, China.
Zhijian XuCancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yehua GanPeking University School and Hospital of Stomatology, Beijing, China. Email: kqyehuagan@bjmu.edu.cn.
Suyun LiCancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. Email: suyunn_li@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesThis study aimed to evaluate vitamin B12 and D levels among long-term vegetarians and to assess the influence of their diet duration and diet subtypes on nutritional status in Beijing, China. METHODS AND STUDY

designA cross-sectional analysis was conducted on 104 vegetarians (84 vegans, 20 lacto-ovo vegetarians). Serum vitamin B12 and D levels were measured, and demographic, dietary, and supplement use data were collected. Statistical analyses included ANOVA, Kruskal-Wallis tests, chi-square tests, and multivariate regressions.

resultsThe prevalence of vitamin B12 deficiency (<200 pg/mL) was 38.5%, with higher rates in vegans (44.1%) than lacto-ovo vegetarians (15.0%, p = 0.021). Vitamin D defi-ciency (<20 ng/mL) affected 84.6% of participants, worsening with longer diet duration (p <0.001), yet showed no significant difference between vegan and lacto-ovo subtypes (85.7% vs 80.0%, p = 0.524). Multivariate analysis revealed negative correlations between diet duration (6-10 years and >10 years) and vita-min B12 and D levels (p <0.05). Lacto-ovo vegetarians showed significantly higher vitamin B12 levels than vegans (p = 0.029), and supplement use improved both vitamins' status (p <0.05).

conclusionsThis study reveals a dual challenge among Beijing long-term vegetarians: vitamin B12 deficiency was strongly associated with the degree of exclusion of animal products from the diet (veganism), while vitamin D deficiency was highly prevalent and worsened with longer diet duration. The near-universal vitamin D deficiency observed in this study suggests that, in the Beijing context, the risk may extend beyond dietary choice, potentially reflecting regional environmental factors; however, this requires confirmation through comparative studies with omnivores controls.

Indexed as

Diet, VegetarianNutritional StatusVegetariansVitamin B 12Vitamin DAdultBeijingChinaCross-Sectional StudiesFemaleHumansMaleMiddle AgedVitamin B 12 DeficiencyVitamin D DeficiencyVitamin B 12Vitamin Ddurationlong-term vegetarianssubtypesvitamin B12vitamin D

Identifiers

PMID41565239
PMCPMC12823248

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.