Evidence map›Paper›PMID 41565228›Full record

SynthesisAsia Pacific journal of clinical nutrition2026

Association of patient-generated subjective global assessment (PG-SGA) scores with survival outcomes in cancer patients: A systematic review and meta-analysis.

Hanhan Wu, Yunshan Fan, Jing Cheng, Xiude Li, Qihong Zhao, Anla Hu, Bao Zhang

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Asia Pacific journal of clinical nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hanhan WuDepartment of Clinical Nutrition, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, PR China.
Yunshan FanDepartment of Clinical Nutrition, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, PR China.
Jing ChengDepartment of Clinical Nutrition, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, PR China.
Xiude LiDepartment of Clinical Nutrition, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, PR China.
Qihong ZhaoDepartment of Nutrition and Food Hygiene, School of Public Health, Anhui Medical University, Hefei, Anhui, PR China.
Anla HuDepartment of Nutrition and Food Hygiene, School of Public Health, Anhui Medical University, Hefei, Anhui, PR China. Email: huanla@ahmu.edu.cn.
Bao ZhangDepartment of Clinical Nutrition, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, PR China. Email: 596255538@qq.com.

Funding

National Key Research and Development Program of China 2020YFC2006502National Natural Science Foundation of China 81973049
6 · The paper itself

Abstract

BACKGROUND AND

objectivesUndernutrition is prevalent among patients with cancer and may be associated with survival. The Patient-Generated Subjective Global Assessment (PG-SGA) is a widely recognised scale for the nutritional assessment of patients with cancer. The relationship between undernutrition, as defined by the PG-SGA, and cancer prognosis has been somewhat controversial, and this meta-analysis sought to clarify this. This meta-analysis was performed to elucidate the association between undernutrition, as defined by the PG-SGA, and survival outcomes in patients with cancer. METHODS AND STUDY

designStudies that investigated the association between undernutrition, defined by the PG-SGA, and survival outcomes in patients with cancer were included, and data were retrieved from PubMed, EMBASE, the Cochrane Library, and Web of Science until October 2023.

resultsA total of 18 prospective and 14 retrospective studies with 27120 cancer patients were identified in this analysis. All studies had high methodological quality, with an average score of 7.66. The results showed that undernutrition, as defined by the PG-SGA, was significantly correlated with worse overall survival (Hazard Ratio (HR) = 1.99, 95% Confidence Interval (CI): 1.62-2.45). Subgroup analyses further confirmed that the pooled HR was 1.64 (95% CI: 1.26-2.13) for moderate undernutrition, which increased gradually in cases of severe undernutrition (HR = 2.65, 95% CI: 2.45-2.87). The degree of undernutrition might be the source of the heterogeneity (p value for the test of subgroup differences was < 0.001). Sensitivity analyses confirmed the robustness and credibility of this meta-analysis.

conclusionsThese results under-score the significant association between undernutrition, as defined by the PG-SGA, and reduced overall survival in patients with cancer. Detection of nutritional status using the PG-SGA may be beneficial for improving survival in patients with cancer.

Indexed as

MalnutritionNeoplasmsNutrition AssessmentHumansNutritional StatusSurvival Analysiscancermeta-analysisPG-SGAsurvivalundernutrition

Identifiers

PMID41565228
PMCPMC12823262

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.