ReviewAdvances in nutrition (Bethesda, Md.)2026
Food and Drug Administration Expert Panel on Infant Formula "Operation Stork Speed" June 2025: Part 1, Nutrient Considerations.
Review in Advances in nutrition (Bethesda, Md.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Charting a New Era to Modernize United States Infant Formula Regulation.Advances in nutrition (Bethesda, Md.) · 2026Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Operation Stork Speed, launched by the Food and Drug Administration in March 2025, represents a comprehensive initiative to update infant formula regulations that have remained largely unchanged since the 1980s. This expert panel review addresses recommendations for nutrients considering 4 decades of accumulated scientific evidence. Current Food and Drug Administration fatty acid regulations specify only total fat content and minimum linoleic acid requirements, despite substantial international consensus on polyunsaturated fatty acid specifications. Evidence strongly supports establishing maximum linoleic acid concentrations and docosahexaenoic acid and arachidonic acid requirements, reflecting the critical role of omega-3 (ω-3) fatty acids in neurocognitive development and visual acuity. The panel emphasizes that saturated and monounsaturated fatty acids comprise over 80% of human milk fatty acids, while acknowledging recent concerns about seed oils and supporting balanced PUFA formulations. Carbohydrate composition presents significant concerns, as over half of United States formulas contain glucose polymers (e.g., corn syrup solids) despite lactose being the primary carbohydrate energy source in human milk. Observational studies have linked corn syrup-based formulas to multiple potential health risks, including excess weight gain, warranting reconsideration of the value of non-lactose carbohydrate substitutions in formulas for healthy children. Protein content recommendations support decreasing the upper range of allowable intake, aligning with European standards and addressing concerns about excessive protein intake contributing to later obesity risk. Micronutrient evaluation reveals the need to reduce the iron content in routine formulas, consistent with European Food Safety Authority recommendations and emerging safety data, and a need to set upper limits for the concentration of calcium and phosphorus. Overall, infant formula is a healthy product that has been successfully feeding infants for many decades. These comprehensive updates aim to more closely align United States infant formula regulations with current scientific understanding and international standards while supporting optimal infant growth, development, and long-term health outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.