ArticleTranslational vision science & technology2026
Selective Retina Therapy With Fundus Image-Based Titration in Central Serous Chorioretinopathy: Prospective Outcomes and Predictive Factors.
Article in Translational vision science & technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Effects of Selective Retina Therapy on Central Serous Chorioretinopathy with Serous Pigment Epithelial Detachments.Journal of clinical medicine · 2026Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: We evaluated the clinical outcomes of selective retina therapy (SRT) with fundus image-based titration approach for central serous chorioretinopathy (CSC). Methods: Sixty eyes (60 participants) with chronic CSC prospectively underwent SRT. Treatment (527-nm wavelength, 1.7-µs pulse duration) targeted leakage sites identified via fundus fluorescein angiography. Pulse energy and micropulse number were adjusted based on test-spot fundus images. Changes in best-corrected visual acuity (BCVA), central foveal thickness, subfoveal choroidal thickness, and subretinal fluid (SRF) height were evaluated at baseline and at 1, 2, and 3 months post treatment. Retinal sensitivity was measured by microperimetry at baseline and 3 months. Outcomes were compared between eyes with completely resolved or residual SRF at 3 months. Results: At 3 months, complete SRF resolution was observed in 80.8% of eyes (42/52). The mean SRF height decreased from 135.6 ± 81.9 µm to 28.0 ± 72.0 µm, and the mean central foveal thickness from 318.9 ± 88.0 µm to 231.9 ± 69.8 µm (both P < 0.001). In parallel, functional parameters also improved, with mean best-corrected visual acuity increasing from 0.17 ± 0.15 logarithm of the minimum angle of resolution to 0.06 ± 0.12 logarithm of the minimum angle of resolution and mean deviation of retinal sensitivity from -0.89 ± 1.65 dB to 0.02 ± 1.29 dB (both P < 0.001). Female sex was significantly associated with persistent SRF in both univariate and multivariable analyses (odds ratio, 30.794; 95% confidence interval, 2.996-774.668; P = 0.011). Conclusions: SRT with fundus image-based titration yielded favorable functional and anatomical outcomes in CSC. Female sex was associated with persistent SRF, although this finding should be interpreted cautiously. Translational Relevance: Fundus image-based titration translates selective retinal pigment epithelium targeting in selective retina therapy into a reproducible clinical approach for central serous chorioretinopathy. This strategy facilitates individualized treatment while remaining compatible with routine clinical practice.
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