ArticleSleep & breathing = Schlaf & Atmung2026
Glossopharyngeal airway collapse is the main factor leading REM-related oxygen desaturation in patients with obstructive sleep apnea: a pilot study.
Article in Sleep & breathing = Schlaf & Atmung, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
objectiveThis study aimed to determine the factors underlying rapid eye movement (REM) sleep-related oxygen desaturation (OD) in patients with obstructive sleep apnea (OSA).
methodsAll subjects underwent overnight polysomnography with synchronous genioglossus electromyography using intraoral surface electrodes. For those subjects diagnosed with moderate or severe OSA (AHI > 15 events/h), we respectively calculated the average OD during rapid eye movement (REM-OD) and non-rapid eye movement sleep (NREM-OD). The ratio of REM-OD/NREM-OD ≥ 1.5 was defined as patients with REM-related OD. The upper airway anatomy was measured by three-dimensional computed tomography (3D-CT) in all subjects. The independent t test was used to analyze the difference between groups.
resultsThirty-three male OSA patients were recruited and divided into two groups, includingthe REM-related OD group (n = 15, AHI 68.01 ± 18.35 events/h) and the NREM-related OD group (n = 18, AHI 57.48 ± 28.81 events/h). The REM-related OD group had a more severe lowest oxygen saturation overnight (56.14 ± 7.06 vs. 70.92 ± 14.49, p = 0.009). GGEMG variables were similar between the two groups, except for apnea time in the REM period (p < 0.001). Parameters measured by 3D-CT of the UA showed that the REM-related OD group had a narrower glossopharyngeal airway, with a smaller minimal anteroposterior airway dimension (12.41 ± 2.99 vs. 17.58 ± 4.78, p = 0.020) and smaller minimal cross-sectional airway area (119.81 ± 30.94 vs. 199.78 ± 75.02, p = 0.005).
conclusionGlossopharyngeal airway narrowing is the leading factor of REM-related OD in paitients with moderate or severe OSA by the prolongation of apnea events during REM sleep.
Indexed as
Identifiers
41563629What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.