Evidence map›Paper›PMID 41563581›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2026

Cerebellar volumes' selective association with MoCA over MMSE: a diagnostic insight into mild cognitive impairment and mild dementia.

Maria Devita, Chiara Ceolin, Chiara Begliomini, Michela Sarlo, Alessandra Coin, Alessandra Bertoldo, Giuseppe Sergi, Daniela Mapelli, Marina De Rui

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Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

Maria DevitaDepartment of General Psychology (DPG), University of Padua, Via Venezia 8, Padua, Italy. maria.devita@unipd.it.ORCID http://orcid.org/0000-0001-5899-8000
Chiara CeolinGeriatrics Unit, Department of Medicine (DIMED), University of Padua, Via Giustiniani 2, Padua, Italy.ORCID http://orcid.org/0000-0001-5064-1672
Chiara BegliominiDepartment of General Psychology (DPG), University of Padua, Via Venezia 8, Padua, Italy.ORCID http://orcid.org/0000-0001-7433-0414
Michela SarloDepartment of Communication Sciences, Humanities and International Studies, University of Urbino Carlo Bo, Via Saffi 15, 61029, Urbino, Italy.ORCID http://orcid.org/0000-0001-6652-7604
Alessandra CoinGeriatrics Unit, Department of Medicine (DIMED), University of Padua, Via Giustiniani 2, Padua, Italy.ORCID http://orcid.org/0000-0003-1687-4493
Alessandra BertoldoDepartment of Information Engineering, University of Padua, Via Gardenigo 6/B, Padua, Italy.ORCID http://orcid.org/0000-0002-6262-6354
Giuseppe SergiGeriatrics Unit, Department of Medicine (DIMED), University of Padua, Via Giustiniani 2, Padua, Italy.ORCID http://orcid.org/0000-0001-9757-856X
Daniela MapelliDepartment of General Psychology (DPG), University of Padua, Via Venezia 8, Padua, Italy.ORCID http://orcid.org/0000-0003-2168-1426
Marina De RuiGeriatrics Unit, Department of Medicine (DIMED), University of Padua, Via Giustiniani 2, Padua, Italy.ORCID http://orcid.org/0000-0003-4966-1312

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLinked to motor control, cerebellum is increasingly recognized for its role in cognition and neurodegenerative disorders.

methodsThis retrospective study investigates associations between cerebellar volumes and cognitive screening tools-the Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA)-in individuals with mild cognitive impairment (MCI) or mild dementia.

resultsMoCA scores showed significant positive correlations with cognitive-related cerebellar regions, particularly the left Crus I lobule (r = 0.40, p = 0.02) and total Crus I volume (r = 0.36, p = 0.04). Regression analysis confirmed associations with the left Crus I (β = 0.08, p = 0.02) and right VIIB lobule (β = 0.033, p = 0.032), while MMSE scores correlated only with right Lobule X thickness (r = -0.35, p = 0.04). DISCUSSION: These findings suggest MoCA may better detect cerebellar-related cognitive impairments, underscoring the importance of including cerebellar evaluation in the early diagnosis of dementia.

Indexed as

CerebellumCognitive DysfunctionDementiaMental Status and Dementia TestsAgedAged, 80 and overFemaleHumansMagnetic Resonance ImagingMaleNeuropsychological TestsOrgan SizeRetrospective StudiesCerebellumCognitive cerebellumMild cognitive impairmentMoCA

Identifiers

PMID41563581
PMCPMC12823735

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.