Evidence map›Paper›PMID 41563431›Full record

ArticleDermatologie (Heidelberg, Germany)2026

[IgA-positive anti-p200 pemphigoid mimicking erythema multiforme].

Greta Ancker, Chiara L Blomen, Nina Booken, Ute Siemann-Harms, Stefan W Schneider

Abstract readCase ReportsEnglish Abstract
In one paragraph

Article in Dermatologie (Heidelberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Greta AnckerKlinik für Dermatologie und Venerologie, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Deutschland.
Chiara L BlomenKlinik für Dermatologie und Venerologie, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Deutschland. c.blomen@uke.de.
Nina BookenKlinik für Dermatologie und Venerologie, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Deutschland.
Ute Siemann-HarmsKlinik für Dermatologie und Venerologie, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Deutschland.
Stefan W SchneiderKlinik für Dermatologie und Venerologie, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-p200 pemphigoid is a rare subepidermal blistering dermatosis with variable clinical manifestations that can mimic other bullous skin diseases. We report the case of a 65-year-old patient presenting with extensive bullae on the palms and soles, as well as mucosal erosions. These findings were initially consistent with a diagnosis of erythema multiforme. Direct immunofluorescence (DIF) revealed linear IgA, IgG, and C3 antibody deposits along the dermoepidermal junction. While indirect immunofluorescence (IIF) on salt split skin demonstrated IgA and IgG antibodies binding on the dermal side of the split, immunoblot analysis revealed the presence of antibodies against the 200-kDa protein p200 as well as against laminin-β4. Based on these findings, the diagnosis of IgA-positive anti-p200 pemphigoid, a very rare variant barely described in literature, was made. This case highlights the importance of thorough differential diagnosis in blistering diseases and emphasizes the diagnostic value of immunohistochemical techniques.

Indexed as

AutoantibodiesErythema MultiformeImmunoglobulin ALamininPemphigoid, BullousAgedDiagnosis, DifferentialHumansMaleSkinAutoantibodiesImmunoglobulin ALamininBlistering autoimmune dermatosisBullous dermatosisImmunofluorescence (direct/indirect)Laminin-β4Laminin-γ1

Identifiers

PMID41563431
PMCPMC13433415

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.