Evidence map›Paper›PMID 41563189›Full record

ArticleJACC. Case reports2026

Transcatheter Tricuspid Valve Replacement in Rheumatic Tricuspid Valve Regurgitation.

Jessica Yang, Gilbert H L Tang, Stamatios Lerakis, Takayuki Onishi, Annapoorna S Kini, Sahil Khera, Lucy M Safi

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jessica YangIcahn School of Medicine at Mount Sinai, New York, New York, USA.
Gilbert H L TangDivision of Cardiology, Mount Sinai Heart Fuster Hospital, Icahn School of Medicine at Mount Sinai, New York, New York, USA; Department of Cardiovascular Surgery, Mount Sinai Health System, Mount Sinai Heart Fuster Hospital, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Stamatios LerakisDivision of Cardiology, Mount Sinai Heart Fuster Hospital, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Takayuki OnishiDivision of Cardiology, Mount Sinai Heart Fuster Hospital, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Annapoorna S KiniDivision of Cardiology, Mount Sinai Heart Fuster Hospital, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Sahil KheraDivision of Cardiology, Mount Sinai Heart Fuster Hospital, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Lucy M SafiDivision of Cardiology, Mount Sinai Heart Fuster Hospital, Icahn School of Medicine at Mount Sinai, New York, New York, USA. Electronic address: lucy.safi@mountsinai.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRheumatic heart disease (RHD) is a leading cause of valvular heart disease worldwide, particularly in developing countries. The mitral and aortic valves are most often affected; however, tricuspid valve involvement has been observed in advanced cases. CASE SUMMARY: We present a case of a patient with RHD with tricuspid valve involvement who successfully underwent transcatheter tricuspid valve replacement (TTVR). DISCUSSION: TTVR is a promising, less-invasive alternative treatment for patients with severe symptomatic tricuspid regurgitation deemed unsuitable for surgery. Despite the increasing adoption of TTVR, patients with RHD are frequently excluded from major clinical trials, leading to limited evidence supporting the use of this intervention in this population. TAKE-HOME MESSAGES: As TTVR technology advances, its application in RHD warrants further exploration. The routine exclusion of RHD patients or pathology from TTVR clinical trials should also be reconsidered.

Indexed as

rheumatic heart diseasetricuspid valvevalve replacement

Identifiers

PMID41563189
PMCPMC13100524

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.