Evidence map›Paper›PMID 41563172›Full record

ArticleJournal of the American College of Cardiology2026

Hospitalizations and Mortality Among Medicare Beneficiaries at Cardiovascular Risk: Disruptions and Recovery From the COVID-19 Pandemic.

Rishi K Wadhera, R J Waken, Fengxian Wang, Jose F Figueroa, Khavya C Avula, E John Orav, Arnold M Epstein, Karen E Joynt Maddox

Abstract read
In one paragraph

Article in Journal of the American College of Cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rishi K WadheraRichard A. and Susan F. Smith Center for Outcomes Research, Boston, Massachusetts, USA; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts USA; Harvard Medical School, Boston, Massachusetts USA.
R J WakenDivision of Biostatistics, Institute for Informatics, Data Science, and Biostatistics, Washington University School of Medicine, St Louis, Missouri, USA; Center for Advancing Health Services, Policy, and Economics Research, Washington University School of Medicine, St Louis, Missouri, USA.
Fengxian WangCenter for Advancing Health Services, Policy, and Economics Research, Washington University School of Medicine, St Louis, Missouri, USA; Cardiovascular Division, Department of Medicine, Washington University School of Medicine, St Louis, Missouri, USA.
Jose F FigueroaDepartment of Health Policy and Management, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Khavya C AvulaCenter for Advancing Health Services, Policy, and Economics Research, Washington University School of Medicine, St Louis, Missouri, USA; Cardiovascular Division, Department of Medicine, Washington University School of Medicine, St Louis, Missouri, USA.
E John OravDivision of General Internal Medicine and Primary Care, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Arnold M EpsteinDepartment of Health Policy and Management, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA; Division of General Internal Medicine and Primary Care, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Karen E Joynt MaddoxCenter for Advancing Health Services, Policy, and Economics Research, Washington University School of Medicine, St Louis, Missouri, USA; Cardiovascular Division, Department of Medicine, Washington University School of Medicine, St Louis, Missouri, USA. Electronic address: kjoyntmaddox@wustl.edu.

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Cardiovascular Health of Low-Income Working-Age Adults in the US: Health Care Access, Policy, and the PandemicR01HL164561 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI Rishi Kumar Wadhera · 2022 to 2026
$3.7M
The Impact of Bundled Payments for Cardiopulmonary Disease on High-Risk PopulationsR01HL143421 · NHLBI · WASHINGTON UNIVERSITY · PI JOYNT MADDOX, KAREN ELLEN · 2019 to 2022
$3.1M
Strategies to Improve the Cardiovascular Health of Rural Working-Age Adults in the United StatesR01HL174549 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI Rishi Kumar Wadhera · 2024 to 2026
$2.3M
The Impact of the ACO REACH Program on Health Outcomes for Patients with Alzheimer's Disease and Related DementiasR01AG089215 · NIA · WASHINGTON UNIVERSITY · PI Karen Ellen Joynt Maddox · 2024 to 2026
$2.1M
Leveraging SNAP Policies to Improve the Cardiovascular Health of Low-Income Adults in the United StatesR01NR021686 · NINR · BETH ISRAEL DEACONESS MEDICAL CENTER · PI Rishi Kumar Wadhera · 2024 to 2026
$2.0M
Rural-Urban Disparities In Spillover Effects of COVID-19U01NR020555 · NINR · WASHINGTON UNIVERSITY · PI JOYNT MADDOX, KAREN ELLEN · 2022 to 2024
$1.5M
Observation Stays and Readmissions for Older Adults: Implications for Medicare PoliciesR01AG063759 · NIA · UNIVERSITY OF WASHINGTON · PI SABBATINI, AMBER KATHLEEN · 2020 to 2023
$1.4M
The Effect of Patient Dementia on Outpatient Clinicians' Performance on Cost Outcomes Under Medicare Value-Based Payment.R21AG065526 · NIA · WASHINGTON UNIVERSITY · PI JOHNSTON, KENTON JAMES · 2020 to 2021
$308k
NCATS NIH HHS UL1 TR002345NHLBI NIH HHS R01 HL143421NHLBI NIH HHS R01 HL164561NHLBI NIH HHS R01 HL174549NIA NIH HHS R01 AG063759NIA NIH HHS R01 AG089215NIA NIH HHS R21 AG065526NINR NIH HHS R01 NR021686NINR NIH HHS U01 NR020555
6 · The paper itself

Abstract

backgroundThe COVID-19 pandemic led to disruptions in cardiovascular care in mid-2020, but less is known about how patterns of care and clinical outcomes changed for older adults with cardiovascular (CV) risk factors and/or established cardiovascular disease (CVD) in the later stages of the pandemic.

objectivesThis study sought to identify changes in utilization of health care services and all-cause mortality among Medicare beneficiaries with CV risk factors or CVD in the "late pandemic" (January 2021 to December 2022) overall and across subgroups based on rurality and social vulnerability index.

methodsThe study included all Medicare fee-for-service and Medicare Advantage beneficiaries with CV risk factors (hypertension, diabetes mellitus, hyperlipidemia) or CVD (coronary heart disease, heart failure, atrial fibrillation, stroke) from January 2018 to December 2022. A Poisson-lognormal regression model was fitted to compare the adjusted incidence rate ratio (aIRR) of acute care visits, outpatient visits, and all-cause mortality during the late pandemic (January 2021 to July 2022) compared with the prepandemic period (January 2018 to December 2019).

resultsThere were 51,355,577 beneficiaries in the prepandemic period and 55,214,638 in the late pandemic period with CV risk factors or CVD. Hospital visit rates were lower in the late pandemic period compared with the prepandemic period (aIRR: 0.918; 95% CI: 0.915-0.922), and declines were evident among rural and urban beneficiaries, as well as across all levels of social vulnerability and in both fee-for-service and Medicare Advantage. In contrast, use of outpatient visits was higher during the late pandemic period (aIRR: 1.141; 95% CI: 1.134-1.149); these increases were on average higher among urban communities and Medicare Advantage beneficiaries. Mortality was higher during the late pandemic period (aIRR: 1.248; 95% CI: 1.240-1.257), and surges in mortality among this population tracked with national COVID-19 mortality. Beneficiaries in the most socially vulnerable communities (aIRR: 1.116; 95% CI: 1.106-1.124) and those covered by Medicare Advantage (aIRR: 1.342; 95% CI: 1.329-1.356) experienced the greatest increase.

conclusionsIn the later stages of the COVID-19 pandemic, among Medicare beneficiaries with CV risk factors or established CVD, hospitalizations were lower than before the pandemic, outpatient care was used more frequently, and mortality was significantly elevated across risk groups and geographies, with the greatest increases seen in vulnerable communities and those covered by Medicare Advantage.

Indexed as

Cardiovascular DiseasesCOVID-19HospitalizationMedicareAgedAged, 80 and overFemaleHeart Disease Risk FactorsHumansMalePandemicsRisk FactorsSARS-CoV-2United Statesall-cause mortalitycardiovascular diseaseclinical riskpandemicruralitysocial vulnerability index

Identifiers

PMID41563172
PMCPMC13071894

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.