Evidence map›Paper›PMID 41562850›Full record

ArticleProteomes2026

The Proteome of

Sarena Banu, P V Anusha, Pedro Beltran-Alvarez, Mohammed M Idris, Katharina C Wollenberg Valero, Francisco Rivero

Erratum issuedAbstract read
In one paragraph

Article in Proteomes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Sarena BanuCentre for Biomedicine, Hull York Medical School, Faculty of Health Sciences, University of Hull, Hull HU6 7RX, UK.ORCID 0000-0002-8923-5724
P V AnushaCSIR-Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad 500-007, Telangana, India.ORCID 0009-0007-7721-679X
Pedro Beltran-AlvarezCentre for Biomedicine, Hull York Medical School, Faculty of Health Sciences, University of Hull, Hull HU6 7RX, UK.ORCID 0000-0001-8136-8963
Mohammed M IdrisCSIR-Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad 500-007, Telangana, India.ORCID 0000-0002-1462-3458
Katharina C Wollenberg ValeroSchool of Biology and Environmental Science, University College Dublin, D04 V1W8 Dublin, Ireland.ORCID 0000-0001-8858-1804
Francisco RiveroCentre for Biomedicine, Hull York Medical School, Faculty of Health Sciences, University of Hull, Hull HU6 7RX, UK.ORCID 0000-0001-5435-6991

Funding

European Research Council 101044202
6 · The paper itself

Abstract

background

methodsSamples were collected from cells developing synchronously on nitrocellulose filters. Proteins were extracted and digested with trypsin, and peptides were analyzed by liquid chromatography-tandem mass spectrometry. Data were processed using Proteome Discoverer™ for protein identification and label-free quantification.

resultsA total of 4502 proteins were identified, of which 1848 (41%) were present across all stages. Pairwise comparisons between adjacent stages revealed clear transitions, the largest ones occurring between the culmination and fruiting body and between the fruiting body and vegetative stage, involving 29% and 52% of proteins, respectively. Hierarchical clustering assigned proteins to one of nine clusters, each displaying a distinct pattern of abundances across the life cycle.

conclusionsThis study presents the first complete developmental proteomic time series for

Indexed as

developmentDictyostelium discoideumfunctional enrichmenthierarchical clusteringlabel-free quantificationmass spectrometryproteomics

Identifiers

PMID41562850
PMCPMC12821622

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.