Evidence map›Paper›PMID 41562831›Full record

ArticleNeuroSci2026

Home-Based REM Sleep Without Atonia in Patients with Parkinson's Disease: A Post Hoc Analysis of the ZEAL Study.

Hiroshi Kataoka, Masahiro Isogawa, Hitoki Nanaura, Hiroyuki Kurakami, Miyoko Hasebe, Kaoru Kinugawa, Takao Kiriyama, Tesseki Izumi, Masato Kasahara, Kazuma Sugie

Abstract read
In one paragraph

Article in NeuroSci, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hiroshi KataokaDepartment of Neurology, Nara Medical University, Kashihara 634-8521, Japan.ORCID 0000-0002-4157-5447
Masahiro IsogawaInstitute for Clinical and Translational Science, Nara Medical University Hospital, Kashihara 634-8521, Japan.ORCID 0009-0006-4323-1871
Hitoki NanauraDepartment of Neurology, Nara Medical University, Kashihara 634-8521, Japan.ORCID 0000-0002-0934-7065
Hiroyuki KurakamiInstitute for Clinical and Translational Science, Nara Medical University Hospital, Kashihara 634-8521, Japan.ORCID 0000-0002-1025-1861
Miyoko HasebeInstitute for Clinical and Translational Science, Nara Medical University Hospital, Kashihara 634-8521, Japan.
Kaoru KinugawaDepartment of Neurology, Nara Medical University, Kashihara 634-8521, Japan.ORCID 0000-0002-9258-9312
Takao KiriyamaDepartment of Neurology, Nara Medical University, Kashihara 634-8521, Japan.ORCID 0000-0002-2282-0849
Tesseki IzumiDepartment of Neurology, Nara Medical University, Kashihara 634-8521, Japan.
Masato KasaharaInstitute for Clinical and Translational Science, Nara Medical University Hospital, Kashihara 634-8521, Japan.ORCID 0000-0002-1833-9075
Kazuma SugieDepartment of Neurology, Nara Medical University, Kashihara 634-8521, Japan.ORCID 0000-0003-0148-4687

Funding

Nara Medical University Clinical Research Grant Programme none
6 · The paper itself

Abstract

REM sleep behavioral disorder (RBD) is of increasing interest in Parkinson's disease (PD). Previous studies exploring the association between REM sleep without atonia (RWA) and clinical PD features or other objective sleep metrics are scarce and have used PSG findings. A mobile electroencephalography (EEG)/electrooculography (EOG) recording system with two channels can objectively measure sleep parameters, including RWA, during natural sleep at home. We investigated whether RWA measured on a portable recording device at home could be associated with clinical PD features or other sleep metrics using baseline data from the ZEAL study. Differences between patients with and without RWA was analyzed using ANCOVA test. REM sleep length was significantly longer in patients with RWA than in those without RWA. A multivariate comparison using ANCOVA showed a significant difference in log-transformed REM sleep duration of patients with RWA after adjustment for potential confounders (adjusted mean difference of 1.203; 95% confidence interval 0.468 to 1.937;

Indexed as

movement disorderparkinsonREMREM sleep behavioral disorderREM sleep without atoniasleep

Identifiers

PMID41562831
PMCPMC12821643

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.