Evidence map›Paper›PMID 41562711›Full record

ArticleDermatopathology (Basel, Switzerland)2025

Increased Expression of Angiopoietin 2 and Tie2 in Rosacea.

Aysin Kaya, Jean-Hilaire Saurat, Nathalie Satta, Gürkan Kaya

Abstract read
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In one paragraph

Article in Dermatopathology (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aysin KayaDepartment of Clinical Pharmacology and Toxicology, University of Geneva, 1211 Geneva, Switzerland.ORCID 0009-0009-5970-4700
Jean-Hilaire SauratDepartment of Clinical Pharmacology and Toxicology, University of Geneva, 1211 Geneva, Switzerland.ORCID 0000-0002-6668-2337
Nathalie SattaDepartment of Clinical Pharmacology and Toxicology, University of Geneva, 1211 Geneva, Switzerland.ORCID 0000-0003-3442-834X
Gürkan KayaDepartments of Dermatology and Clinical Pathology, University Hospital of Geneva, 4, Rue Gabrielle-Perret-Gentil, 1211 Geneva, Switzerland.ORCID 0000-0003-4957-549X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study we evaluated the expression of Angiopoietin 1, Angiopoietin 2, and Tie2 by immunohistochemistry in the skin of 10 patients with erythemato telangiectatic and papulopustular rosacea. Significantly increased expression of Tie2 and Angiopoietin 2 in the endothelial cells of the dermal vessels in rosacea skin vs. non-lesional skin (100% and 33.3% for Tie2, and 100% and 50% for Angiopoietin 2) was observed. There was no difference in the expression of Angiopoietin 1 and phosphorylated Tie2 (pTie2) between the lesional skin of rosacea and non-lesional skin.

Indexed as

Angiopoietin 1Angiopoietin 2immunohistochemistrypTie2rosaceaTie2

Identifiers

PMID41562711
PMCPMC12821430

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.