Evidence map›Paper›PMID 41562666›Full record

ReviewInfectious disease reports2026

Diagnostic Accuracy of Utilizing Artificial Intelligence for Malaria Diagnostic: A Systematic Review and Meta-Analysis.

Icha Farihah Deniyati Faratisha, Khadijah Cahya Yunita, Hanifa Rizky Rahmawati, Loeki Enggar Fitri, Nuning Winaris, Lailil Muflikah

Abstract readReview
In one paragraph

Review in Infectious disease reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. NN-assisted image analysis for quantifying intracellularFrontiers in cellular and infection microbiology · 2026
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Icha Farihah Deniyati FaratishaMaster Program in Biomedical Science, Faculty of Medicine, Universitas Brawijaya, Malang 65145, Indonesia.ORCID 0000-0002-6767-5577
Khadijah Cahya YunitaATOM Research Group, Faculty of Medicine, Universitas Brawijaya, Malang 65145, Indonesia.ORCID 0000-0002-7641-5531
Hanifa Rizky RahmawatiATOM Research Group, Faculty of Medicine, Universitas Brawijaya, Malang 65145, Indonesia.ORCID 0009-0007-1242-773X
Loeki Enggar FitriATOM Research Group, Faculty of Medicine, Universitas Brawijaya, Malang 65145, Indonesia.ORCID 0000-0002-4880-1048
Nuning WinarisATOM Research Group, Faculty of Medicine, Universitas Brawijaya, Malang 65145, Indonesia.ORCID 0000-0001-5941-7095
Lailil MuflikahDepartment of Informatics Engineering, Faculty of Computer Science, Universitas Brawijaya, Malang 65145, Indonesia.ORCID 0000-0001-7903-0576

Funding

Ministry of Higher Education, Science and Technology of the Republic of Indonesia 00659/UN10.A0501/B/PT.01.03.2/2025
6 · The paper itself

Abstract

backgroundMalaria remains a major public health concern around the world. Microscopic blood smear examination continues to be the gold standard for diagnosis; however, it requires high technical skills and expertise, limiting diagnostic accuracy in resource-poor settings. Artificial intelligence (AI) has emerged as a promising tool to support malaria detection. This systematic review provides an overview of the diagnostic performance of AI-based systems for malaria diagnosis in a clinical setting.

methodsThis study followed the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines and involved articles within the last 10 years that were collected from PubMed, ScienceDirect, Cochrane, EBSCO, and Wiley Online Library. Original articles that reported AI diagnostic accuracy with external validation were involved. The quality of each study was evaluated using the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2).

resultsTen studies with 6754 patients were analyzed. Pooled results of sensitivity [87.7% (95% CI: 78.2-93.4)] and specificity [91.4% (95% CI: 77.3-97.1)] revealed how much the AI agrees with each method when that method is used as a gold standard. Additionally, AI achieved a sensitivity of 87.7% and a specificity of 91.4% compared to microscopy examination and a sensitivity of 90.7% and a specificity of 88.3% compared to polymerase chain reaction (PCR).

conclusionsAI-based systems improve malaria diagnosis by providing high accuracy, automation, and lower costs. Showing performance comparable to reference methods such as microscopy and PCR, AI is a promising complementary tool for malaria control.

Indexed as

artificial intelligencediagnostic accuracymalariamicroscopypolymerase chain reaction

Identifiers

PMID41562666
PMCPMC12821690

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.