Evidence map›Paper›PMID 41562660›Full record

ArticleInfectious disease reports2026

An Unusual Case of

Maria Gori, Giorgia Orsani, Carlotta Ortelli, Erika Scaltriti, Luca Bolzoni, Luigi Vezzosi, Silvia Bianchi, Clara Fappani, Daniela Colzani, Antonella Amendola and 4 more

Abstract readCase Reports
In one paragraph

Article in Infectious disease reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Maria GoriDepartment of Health Sciences, Università degli Studi di Milano, 20133 Milan, Italy.ORCID 0000-0001-6478-2791
Giorgia OrsaniDepartment of Neurology, University of Milano-Bicocca, San Gerardo Hospital, ASST Monza, 20900 Monza, Italy.ORCID 0009-0009-6515-4100
Carlotta OrtelliDepartment of Neurology, University of Milano-Bicocca, San Gerardo Hospital, ASST Monza, 20900 Monza, Italy.ORCID 0000-0002-1579-9834
Erika ScaltritiRisk Analysis and Genomic Epidemiology Unit, Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia-Romagna, 43126 Parma, Italy.ORCID 0000-0003-2499-5930
Luca BolzoniRisk Analysis and Genomic Epidemiology Unit, Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia-Romagna, 43126 Parma, Italy.ORCID 0000-0001-8523-4460
Luigi VezzosiDirectorate General for Health of the Lombardy Region, 20124 Milan, Italy.ORCID 0000-0001-6461-2231
Silvia BianchiDepartment of Health Sciences, Università degli Studi di Milano, 20133 Milan, Italy.ORCID 0000-0002-1365-9408
Clara FappaniDepartment of Health Sciences, Università degli Studi di Milano, 20133 Milan, Italy.ORCID 0000-0002-1573-5531
Daniela ColzaniDepartment of Health Sciences, Università degli Studi di Milano, 20133 Milan, Italy.ORCID 0000-0002-4079-1957
Antonella AmendolaDepartment of Health Sciences, Università degli Studi di Milano, 20133 Milan, Italy.ORCID 0000-0002-0499-8977
Danilo CeredaDirectorate General for Health of the Lombardy Region, 20124 Milan, Italy.ORCID 0000-0001-5945-5710
Laura MarzoratiDepartment of Neurology, University of Milano-Bicocca, San Gerardo Hospital, ASST Monza, 20900 Monza, Italy.
Stefano PongoliniRisk Analysis and Genomic Epidemiology Unit, Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia-Romagna, 43126 Parma, Italy.ORCID 0000-0002-4823-3562
Elisabetta TanziDepartment of Health Sciences, Università degli Studi di Milano, 20133 Milan, Italy.ORCID 0000-0002-4119-701X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectives

methodsDiagnostic evaluation included neuroimaging, blood cultures, and microbiological investigations, followed by antimicrobial treatment according to available evidence. The isolated Lm strain underwent whole genome sequencing. Dietary history was also collected.

resultsPositive early blood cultures were pivotal in identifying Lm as the aetiological agent. Neuroimaging revealed brain abscesses consistent with neurolisteriosis. The clinical course was complicated by pneumonia and opportunistic co-infecting pathogens, and despite adequate treatment according to the available literature, the outcome was fatal. Genomic characterisation revealed that the patient was infected with an strain belonged to the sequence type 206 and clonal complex 14, described as hypervirulent. The patient reported consuming several foods known to be associated with an increased risk of listeriosis.

conclusionsThis case highlights the challenges involved in diagnosing and managing listerial brain abscesses, particularly in elderly patients. Even when the primary central nervous system infection is under control, the prognosis may be significantly impacted by comorbid conditions and hospital-related complications rather than the infection itself. Our findings underscore the need for improved preventive strategies and targeted risk communication regarding high-risk foods, particularly among elderly populations.

Indexed as

cerebral abscessesfoodborne pathogenslisteriosissurveillance

Identifiers

PMID41562660
PMCPMC12821487

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.