ArticleMicrobiology spectrum2026
Performance evaluation of GenXplore q4800: a novel open-platform automated nucleic acid testing system.
Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
13 authors.
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Abstract
The emergence of diverse infectious diseases has led to the development of numerous molecular diagnostic kits for pathogen detection. These nucleic acid testing kits are typically categorized as manual or automated, with most automated kits requiring proprietary instruments, thereby limiting flexibility. GenXplore q4800 is a newly developed, open-platform, fully automated nucleic acid testing system designed to be compatible with a wide range of manual testing kits from different manufacturers. In this study, we evaluated the analytical and clinical performance of the GenXplore q4800 using manual molecular kits targeting sexually transmitted infections and respiratory viruses. The automated detection of inactivated pathogen controls demonstrated high repeatability, reproducibility, and sensitivity. The result of the contamination assessment was acceptable. For clinical validation, 120 urine specimens were tested for
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