Evidence map›Paper›PMID 41562574›Full record

ArticleJournal of medical virology2026

Integrated Genomic and Epidemiological Surveillance to Monitor SARS-CoV-2 Variants in Italy: Insights From the JN.1 Case Study (2023-2024).

Mattia Manica, Emanuela Giombini, Martina Del Manso, Carla Molina Grané, Luigina Ambrosio, Antonino Bella, Angela di Martino, Daniele Petrone, Flavia Riccardo, Piero Poletti and 4 more

Abstract read
In one paragraph

Article in Journal of medical virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mattia ManicaCenter for Health Emergencies, Fondazione Bruno Kessler, Trento, Italy.ORCID https://orcid.org/0000-0003-3709-1199
Emanuela GiombiniDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Martina Del MansoDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Carla Molina GranéCenter for Health Emergencies, Fondazione Bruno Kessler, Trento, Italy.ORCID https://orcid.org/0000-0002-4071-7159
Luigina AmbrosioDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.ORCID https://orcid.org/0000-0002-9063-3973
Antonino BellaDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Angela di MartinoDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Daniele PetroneDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Flavia RiccardoDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Piero PolettiCenter for Health Emergencies, Fondazione Bruno Kessler, Trento, Italy.
Patrizio PezzottiDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Anna Teresa PalamaraDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Stefano MerlerCenter for Health Emergencies, Fondazione Bruno Kessler, Trento, Italy.
Paola StefanelliDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.

Funding

NextGenerationEU-MUR CUP H93C22000640007NextGenerationEU-MUR PE00000007SeCOV+ 101102366
6 · The paper itself

Abstract

The epidemiology of SARS-CoV-2 is marked by the continuous emergence of new lineages. Early detection and assessment of their transmissibility can be challenging for surveillance systems that rely solely on case time series data. Genomic surveillance, focusing on identifying and characterizing circulating variants, can provide early insights into their epidemiological impact. Phylogenetic and phylodynamic methods were applied to sequence data collected between October 2023 and January 2024 to study the transmission of the JN.1 variant in Italy. The genomic surveillance encompassed two data flows: flash surveys estimating variant prevalence and continuous sampling to identify emerging variants. We estimated the effective reproduction number (R

Indexed as

COVID-19Epidemiological MonitoringSARS-CoV-2Genome, ViralGenomicsHumansItalyPhylogenyepidemiologyGeneticsSARS coronavirusVirus classification

Identifiers

PMID41562574
PMCPMC12822238

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.