Evidence map›Paper›PMID 41562486›Full record

ArticleEnvironmental science & technology2026

Evaluating Legacy and Emerging PFAS in Human Blood Collected from 2003 to 2021.

Gregory P Kudzin, James N Dodds, Kaylie I Kirkwood-Donelson, Adam Schiffenbauer, Kakali Sarkar, Payam Noroozi Farhadi, Frederick W Miller, Dylan Johnson, Jessie Chappel, Alan K Jarmusch and 2 more

Abstract read
In one paragraph

Article in Environmental science & technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Gregory P KudzinDepartment of Chemistry, University of North Carolina, Chapel Hill, North Carolina 27599, United States.ORCID 0009-0007-0687-3733
James N DoddsDepartment of Chemistry, University of North Carolina, Chapel Hill, North Carolina 27599, United States.ORCID 0000-0002-9702-2294
Kaylie I Kirkwood-DonelsonImmunity, Inflammation, and Disease Laboratory, Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, United States.ORCID 0000-0003-3248-820X
Adam SchiffenbauerEnvironmental Autoimmunity Group, Clinical Research Branch, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Bethesda, Maryland 20892, United States.ORCID 0000-0001-9964-9966
Kakali SarkarEnvironmental Autoimmunity Group, Clinical Research Branch, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Bethesda, Maryland 20892, United States.
Payam Noroozi FarhadiEnvironmental Autoimmunity Group, Clinical Research Branch, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Bethesda, Maryland 20892, United States.
Frederick W MillerEnvironmental Autoimmunity Group, Clinical Research Branch, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Bethesda, Maryland 20892, United States.
Dylan JohnsonIntegrative Bioinformatics Support Group, Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, United States.
Jessie ChappelDepartment of Environmental Sciences and Engineering (ESE), Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Alan K JarmuschImmunity, Inflammation, and Disease Laboratory, Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, United States.ORCID 0000-0002-2228-6308
Lisa G RiderEnvironmental Autoimmunity Group, Clinical Research Branch, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health (NIH), Bethesda, Maryland 20892, United States.
Erin S BakerDepartment of Chemistry, University of North Carolina, Chapel Hill, North Carolina 27599, United States.ORCID 0000-0001-5246-2213

Funding

Environmental/genetic Risk Factors and Pathogenesis of Autoimmune DiseaseZIAES101074 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI RIDER, LISA · 2009 to 2025
$34.6M
Single cell, multi-parametric high throughput platform to classify endocrine disruptor potential of mixturesP42ES027704 · NIEHS · TEXAS A&M UNIVERSITY · PI Efstratios Pistikopoulos · 2017 to 2026
$21.2M
Integrative BioinformaticsZICES103371 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI LI, JIAN-LIANG · 2022 to 2025
$11.5M
Mass Spectrometry-based Untargeted MetabolomicsZICES103363 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI JARMUSCH, ALAN · 2021 to 2025
$6.5M
SCIENTIFIC, OPERATIONS, AND ADMINISTRATIVE RESOURCES (SOAR) TO NIH.75N95021D00012 · NIDA · KELLY SERVICES, INC. · PI SPROSE, SARA · 2021 to 2021
$57k
Intramural NIH HHS ZIA ES101074Intramural NIH HHS ZIC ES103363Intramural NIH HHS ZIC ES103371NIDA NIH HHS 75N95021D00012NIEHS NIH HHS P42 ES027704
6 · The paper itself

Abstract

Per- and polyfluoroalkyl substances (PFASs) are a class of manmade chemicals linked to numerous health outcomes including cancers and increased cholesterol. Consequently, legacy PFASs such as perfluorooctanesulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) have been voluntarily phased out of production within the United States since the early 2000s. However, as replacements, emerging PFASs have been introduced over the last 25 years. The presence and accumulation of these emerging PFASs remains largely unexplored due to the complexity of their identification and quantification. Here, we analyzed a unique set of serum samples (

Indexed as

FluorocarbonsAlkanesulfonic AcidsCaprylatesEnvironmental PollutantsHumansAlkanesulfonic AcidsCaprylatesEnvironmental PollutantsFluorocarbonsperfluorooctane sulfonic acidperfluorooctanoic acid6:2 DiPAP9Cl-PF3ONSchlorinated PFASF-53Bnon-targetedsuspect screening

Identifiers

PMID41562486
PMCPMC12826319

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.