Evidence map›Paper›PMID 41562274›Full record

ArticleMolecular ecology2026

Genomic Architecture of Inbreeding Depression Associated With Hatching Failure in an Endangered Parrot.

Yasmin Foster, Stefanie Grosser, Brodie J Foster, Nicolas Dussex, Aimee Stubbs, Ludovic Dutoit, Theo Atkinson, Fiona Robertson, Ken G Dodds, Rudiger Brauning and 3 more

Abstract read
In one paragraph

Article in Molecular ecology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yasmin FosterDepartment of Zoology, University of Otago, Dunedin, New Zealand.ORCID https://orcid.org/0000-0002-0377-1244
Stefanie GrosserDepartment of Zoology, University of Otago, Dunedin, New Zealand.ORCID https://orcid.org/0000-0002-1524-7255
Brodie J FosterDepartment of Zoology, University of Otago, Dunedin, New Zealand.ORCID https://orcid.org/0000-0002-1467-0078
Nicolas DussexDepartment of Population Analysis and Monitoring, Swedish Museum of Natural History, Stockholm, Sweden.ORCID https://orcid.org/0000-0002-9179-8593
Aimee StubbsDepartment of Zoology, University of Otago, Dunedin, New Zealand.ORCID https://orcid.org/0000-0002-4123-4474
Ludovic DutoitDepartment of Zoology, University of Otago, Dunedin, New Zealand.ORCID https://orcid.org/0000-0002-0164-9878
Theo AtkinsonDepartment of Zoology, University of Otago, Dunedin, New Zealand.ORCID https://orcid.org/0009-0001-4876-7433
Fiona RobertsonDepartment of Zoology, University of Otago, Dunedin, New Zealand.
Ken G DoddsAgResearch, Mosgiel, New Zealand.ORCID https://orcid.org/0000-0002-9347-6379
Rudiger BrauningAgResearch, Mosgiel, New Zealand.ORCID https://orcid.org/0000-0001-5068-9166
Jeanne M E JacobsAgResearch, Mosgiel, New Zealand.ORCID https://orcid.org/0000-0002-1047-1039
John C McEwanAgResearch, Mosgiel, New Zealand.ORCID https://orcid.org/0000-0003-4801-6207
Bruce C RobertsonDepartment of Zoology, University of Otago, Dunedin, New Zealand.ORCID https://orcid.org/0000-0002-5348-2731

Funding

Marsden Fund UOO1817Ministry for Business Innovation and Employment C10X1306
6 · The paper itself

Abstract

Conservation management of endangered species increasingly relies on genomic approaches to understand how long-term small population sizes affect the fitness of extant individuals. However, despite the growing investment in genomic resources by conservation programmes, the impact that sequencing methods have on the ability to detect inbreeding-related phenomena has been largely overlooked. Here, we compare the use of whole-genome and reduced-representation sequencing approaches in 148 individuals of the critically endangered parrot, the kākāpō (Strigops habroptilus), to assess inbreeding and its effects on female reproductive success. We explore how sequencing choice influences the identification of long stretches of homozygosity across the genome (runs of homozygosity, ROH), and compare the conservation implications of the results produced by each method. Both whole-genome and reduced-representation sequencing approaches provided comparable estimates of genome-wide inbreeding (F

Indexed as

Endangered SpeciesGenetics, PopulationInbreeding DepressionParrotsAnimalsConservation of Natural ResourcesFemaleGenomeGenomicsHomozygoteInbreedingReproductionSequence Analysis, DNAWhole Genome Sequencingconservation managementhatching successinbreedinginbreeding depressionreproductive successruns of homozygosity

Identifiers

PMID41562274
PMCPMC12820920

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.