Evidence map›Paper›PMID 41562225›Full record

ArticleInternational journal of methods in psychiatric research2026

Development and Comparability of Internalizing and Externalizing Symptom Spectra From Adolescence to Young Adulthood.

Vera Birgel, Michael Rapp, Mira Tschorn, Heike Hölling, Caroline Cohrdes

Abstract read
In one paragraph

Article in International journal of methods in psychiatric research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vera BirgelDepartment of Epidemiology and Health Monitoring, Robert Koch Institute, Berlin, Germany.ORCID 0000-0001-8879-085X
Michael RappGerman Center for Mental Health (DZPG), Berlin, Germany.
Mira TschornGerman Center for Mental Health (DZPG), Berlin, Germany.
Heike HöllingDepartment of Epidemiology and Health Monitoring, Robert Koch Institute, Berlin, Germany.
Caroline CohrdesDepartment of Epidemiology and Health Monitoring, Robert Koch Institute, Berlin, Germany.

Funding

Federal Ministry of Research, Technology and Space 01EE2301 F
6 · The paper itself

Abstract

objectivesThis study examines the continuity and comparability of internalizing and externalizing symptom spectra from adolescence to young adulthood, addressing measurement challenges across developmental stages. Leveraging the Hierarchical Taxonomy of Psychopathology (HiTOP) framework, it explores whether symptom spectra in adolescence predict corresponding symptoms in young adulthood.

methodsData were drawn from JEPSY, a follow-up of the national KiGGS cohort (N = 2172, age 18-26). Adolescent internalizing and externalizing symptoms were assessed via the Strengths and Difficulties Questionnaire (SDQ) and substance use items. Adult outcomes included the Patient Health Questionnaire (PHQ-4), DSM-5 Cross-Cutting Symptom Measure (DSM-5 CC), and Personality Inventory for DSM-5 (PID-5). Factor analyses assessed structural consistency, and robust regression examined associations between adolescent and adult symptom spectra over 7-10 years.

resultsA four-factor model best captured the SDQ structure. In young adulthood, three spectra emerged: internalizing symptoms, externalizing traits, and substance use. Adolescent emotional and peer problems predicted internalizing symptoms in adulthood. Conduct problems and hyperactivity predicted externalizing traits. Substance use was associated with hyperactivity, smoking, and risky drinking-but negatively with peer problems.

conclusionThe findings support the continuity of broad psychopathological spectra and demonstrate that harmonized approaches can bridge measurement gaps and enhance longitudinal comparability.

Indexed as

Behavioral SymptomsSubstance-Related DisordersAdolescentAdultFemaleFollow-Up StudiesHumansMaleYoung Adultexternalizing symptomsHiTOPinternalizing symptomsmeasurement comparabilitytransition to adulthood

Identifiers

PMID41562225
PMCPMC12820720

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.