Evidence map›Paper›PMID 41562112›Full record

ArticleJBMR plus2026

Repeatability of objective bone and joint measures in the knee using weight-bearing computed tomography: three-dimensional quantification of bone mineral density, joint space width, and subchondral bone plate thickness.

Tadiwa H Waungana, Ria Mangat, Chloe Chen, Ainsley C J Smith, Yousif Al-Khoury, Michael T Kuczynski, Tom Turmezei, Donald D Anderson, William Brent Edwards, Sarah L Manske

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JBMR plus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tadiwa H WaunganaDepartment of Biomedical Engineering, University of Calgary, Calgary, AB T2N 4V8, Canada.ORCID https://orcid.org/0000-0002-0430-4242
Ria MangatMcCaig Institute for Bone and Joint Health, University of Calgary, Calgary, AB T2N 4Z6, Canada.
Chloe ChenMcCaig Institute for Bone and Joint Health, University of Calgary, Calgary, AB T2N 4Z6, Canada.
Ainsley C J SmithDepartment of Biomedical Engineering, University of Calgary, Calgary, AB T2N 4V8, Canada.
Yousif Al-KhouryDepartment of Biomedical Engineering, University of Calgary, Calgary, AB T2N 4V8, Canada.
Michael T KuczynskiMcCaig Institute for Bone and Joint Health, University of Calgary, Calgary, AB T2N 4Z6, Canada.ORCID https://orcid.org/0000-0001-5671-1205
Tom TurmezeiDepartment of Radiology, Norfolk and Norwich University Hospital, Norwich, NR4 7UY, United Kingdom.
Donald D AndersonDepartment of Orthopedics and Rehabilitation, University of Iowa, Iowa City, IA 52242, United States.ORCID https://orcid.org/0000-0002-1640-6107
William Brent EdwardsDepartment of Biomedical Engineering, University of Calgary, Calgary, AB T2N 4V8, Canada.ORCID https://orcid.org/0000-0002-3623-9764
Sarah L ManskeDepartment of Biomedical Engineering, University of Calgary, Calgary, AB T2N 4V8, Canada.ORCID https://orcid.org/0000-0003-0888-9556

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone alterations and degenerative joint structural changes are frequently observed in knee osteoarthritis (OA). Objective measures of subchondral bone plate thickness (SBP.Th), apparent BMD, and joint space width (JSW) have begun to be used to better assess and understand disease progression. Weight-bearing CT (WBCT) allows 3D assessment of multiple bone and joint parameters; however, there is a paucity of literature investigating factors that might affect our ability to track changes over time. The purpose of this study was to investigate the repeatability of BMD, JSW, and SBP.Th measures obtained from WBCT images. Same-day, scan-rescan, knee WBCT images were acquired from 37 healthy adults (20 female, mean age: 24.6 yr). We quantified trabecular bone BMD at the proximal tibia and implemented joint space and cortical bone mapping to measure tibiofemoral JSW and SBP.Th, respectively. Test-retest repeatability was evaluated using coefficients of variation (CV

Indexed as

BMDjoint space widthkneeosteoarthritisrepeatabilitysubchondral boneweight-bearing CT

Identifiers

PMID41562112
PMCPMC12815259

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.