Evidence map›Paper›PMID 41562066›Full record

ReviewFrontiers in immunology2025

Decoding the immunoregulatory functions of ALKBH5 in the tumor microenvironment.

Chunhong Li, Xiulin Jiang, Yixiao Yuan, Qiang Wang

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. The relevance of mJournal of cancer research and clinical oncology · 2026
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chunhong LiDepartment of Oncology, Suining Central Hospital, Suining, Sichuan, China.
Xiulin JiangDepartment of Systems Biology, City of Hope Comprehensive Cancer Center Biomedical Research Center, Monrovia, CA, United States.
Yixiao YuanDepartment of Systems Biology, City of Hope Comprehensive Cancer Center Biomedical Research Center, Monrovia, CA, United States.
Qiang WangDepartment of Gastrointestinal Surgical Unit, Suining Central Hospital, Suining, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

N

Indexed as

AlkB Homolog 5, RNA DemethylaseNeoplasmsTumor MicroenvironmentAdenosineAnimalsEpitranscriptomeGene Expression Regulation, NeoplasticHumansRNA MethylationAdenosineALKBH5 protein, humanAlkB Homolog 5, RNA DemethylaseN-methyladenosineALKBH5cancer immunotherapyimmune checkpointm6A demethylasetumor microenvironment

Identifiers

PMID41562066
PMCPMC12812893

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.