SynthesisFrontiers in psychiatry2025
Prevalence of depression and anxiety with premature ejaculation and its four subtypes: a systematic review and meta-analysis.
Synthesis in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- The relationship between the severity of erectile dysfunction and the risk of co-occurrence with premature ejaculation: a cross-sectional study.Frontiers in public health · 2026Article
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5 authors.
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Abstract
Background: Premature ejaculation (PE) is a common male sexual dysfunction and is frequently accompanied by psychological comorbidities such as anxiety and depression. However, the extent of these mental health burdens across different PE subtypes remains unclear. Aims: The aims of this study were to estimate the pooled prevalence of anxiety and depression among men with PE and to compare prevalence patterns across the four established PE subtypes: acquired PE (APE), lifelong PE (LPE), premature-like ejaculatory dysfunction (PLED), and natural variable PE (NVPE). Methods: We systematically searched PubMed, Embase, Web of Science, Cochrane Library, CENTRAL, and Springer databases through July 2025 for observational studies reporting anxiety and/or depression in PE populations. Pooled prevalence estimates were calculated using random-effects meta-analyses with Freeman-Tukey double-arcsine transformation. Heterogeneity was quantified using Results: Eighteen studies were included. The pooled prevalence was 42% (95% CI: 25%-61%) for anxiety and 41% (95% CI: 27%-56%) for depression, with substantial heterogeneity ( Conclusion: Anxiety and depression are highly prevalent among men with PE, with notable variation across clinical subtypes. These findings underscore the importance of subtype-aware psychological assessment and individualized management in PE care. Systematic Review Registration: https://www.crd.york.ac.uk/prospero/, identifier CRD42024538434.
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