Trial reportFrontiers in psychiatry2025
Effects of computer-assisted cognitive behavioral therapy on anxiety in patients undergoing functional endoscopic sinus surgery: an exploratory fNIRS study of prefrontal hemodynamic functions.
Trial report in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Perioperative Anxiety in Adults: A Narrative Review of Pathophysiology, Assessment, and Multimodal Management Strategies.Healthcare (Basel, Switzerland) · 2026Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: We investigated prefrontal cortex (PFC) activation in patients undergoing functional endoscopic sinus surgery (FESS) who presented with anxiety, and we evaluated the effect of a computer-assisted cognitive behavioral therapy (cCBT) intervention using functional near-infrared spectroscopy (fNIRS). Methods: Sixty patients scheduled for FESS were randomly assigned to either the active control (AC) group (n = 30) that received health education or the cCBT group (n = 30) that received cCBT. Prefrontal hemodynamic responses were assessed using fNIRS during the performance of the verbal fluency task (VFT). Levels of anxiety, depression, and insomnia were measured at multiple perioperative time points. Results: The cCBT group exhibited a significantly greater number of activated channels than the AC group (37 Discussion: Anxiety in patients undergoing FESS was associated with reduced PFC activation during the VFT. The cCBT intervention improved clinical symptoms and enhanced PFC hemodynamic function. cCBT serves as an effective non-pharmacological intervention for mitigating anxiety and insomnia in this patient population. Clinical Trial Registration: ClinicalTrials.gov, identifier ChiCTR2500113914.
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