ArticleFrontiers in medicine2025
A study on the association between smoking, periodontal inflammation and alveolar bone resorption in patients with chronic periodontitis based on biomarkers: a meta-analysis.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Salivary RANKL/OPG and Periodontal Status Among Users of Heated Tobacco and Electronic Cigarettes Versus Non-Smokers: A Prospective Observational Study.Healthcare (Basel, Switzerland) · 2026Article
- Discordance in the 2018 Periodontal Classification: Conceptual Challenges and a Biologically Grounded Framework for Interpretation.Dentistry journal · 2026Article
- Article
- A study on the association between smoking, periodontal inflammation and alveolar bone resorption in patients with chronic periodontitis based on biomarkers: a meta-analysis.Frontiers in medicine · 2025Article
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Authors and funding
5 authors.
Funding
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Abstract
Objective: To systematically evaluate the association between smoking and both periodontal inflammation and alveolar bone resorption in patients with chronic periodontitis. Methods: A computerized search was conducted using databases such as PubMed, Embase, Web of Science, and China National Knowledge Infrastructure to identify studies published between January 2005 and January 2023 that examined the relationship between smoking and both periodontal inflammation and alveolar bone resorption in chronic periodontitis. A total of 1,654 articles were initially retrieved. After applying the inclusion and exclusion criteria, 13 studies were included in the final analysis, comprising a total of 1,653 patients-893 in the study group and 760 in the control group. The study group included smoker chronic periodontitis patients, and the control group included non-smoker chronic periodontitis patients. Two independent researchers screened the literature and extracted relevant data. Meta-analysis was performed using RevMan 5.3 software. Results: Compared with the control group, the study group showed significantly higher levels of intercellular adhesion molecule 1 (mean difference [MD] = 135.93; 95% confidence interval [CI]: 48.91, 222.95; Conclusion: Smoking exacerbates periodontal inflammation and promotes alveolar bone resorption in patients with chronic periodontitis.
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