ArticleFrontiers in medicine2025
Diffuse large B-cell lymphoma with intussusception in adults: a case report and literature review.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Intussusception secondary to gastrointestinal diffuse large B-cell lymphoma (DLBCL) is exceedingly rare in adults. We present a case of a 23-year-old male admitted with abdominal pain as the primary symptom. Computed tomography (CT) revealed an ileocolic intussusception involving the ascending and transverse colon, demonstrating a characteristic "target." Conservative treatment (including air enema) was ineffective, and the patient finally received surgical treatment. The resected lesion was pathologically confirmed as DLBCL. The patient received postoperative chemotherapy with the R-CHOP regimen. At the 5-month follow-up, no complications or evidence of lymph node involvement elsewhere was observed. Adult intussusception patients should be highly alert to the possibility of malignant tumors, especially lymphoma. Early diagnosis and standardized comprehensive treatment are critical for improving long-term prognosis.
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