Evidence map›Paper›PMID 41561675›Full record

ArticleGynecologic oncology reports2026

Treatment delay and prolongation in locally advanced cervical cancer.

Maya Gross, Joyce Y Wang, Barbara A Goff, Ting Martin Ma, Kylie H Kang, Kemi M Doll, Soledad Jorge

Abstract read
In one paragraph

Article in Gynecologic oncology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maya GrossUniversity of Washington, Department of Obstetrics and Gynecology, Seattle, WA, United States.
Joyce Y WangUniversity of Washington, Department of Obstetrics and Gynecology, Seattle, WA, United States.
Barbara A GoffUniversity of Washington, Department of Obstetrics and Gynecology, Seattle, WA, United States.
Ting Martin MaUniversity of Washington, Department of Radiation Oncology, Seattle, WA, United States.
Kylie H KangUniversity of Washington, Department of Radiation Oncology, Seattle, WA, United States.
Kemi M DollUniversity of Washington, Department of Obstetrics and Gynecology, Seattle, WA, United States.
Soledad JorgeUniversity of Washington, Department of Obstetrics and Gynecology, Seattle, WA, United States.

Funding

TRAINING IN CANCER BIOLOGY &TRANSPLANTATIONT32CA009515 · NCI · UNIVERSITY OF WASHINGTON · PI NANCY ELLEN DAVIDSON, Effie W Petersdorf · 1985 to 2026
$16.2M
NCI NIH HHS T32 CA009515
6 · The paper itself

Abstract

Objectives: Prolonged chemoradiation (CRT) duration predicts inferior survival in locally advanced cervical cancer (LACC). Pre-treatment delays and causes of prolonged treatment duration are less characterized. We aimed to quantify delays across the care continuum and identify predictors of delayed CRT initiation and treatment prolongation. Methods: In this retrospective cohort study, we evaluated LACC patients receiving definitive CRT from 2013 to 2024 at an NCI-designated Cancer Center. We assessed care intervals and sociodemographic/clinical variables. Primary outcome was total patient delay (diagnosis to CRT completion), subdivided into delayed treatment initiation (>75th percentile from diagnosis to CRT) and prolonged CRT duration (>56 days). Secondary outcomes included predictors of delay / prolongation (x Results: Among 92 patients, median time to CRT initiation was 49 days (IQR 40-62) and median treatment duration was 57 days (IQR 52-60). Treatment delay or prolongation was associated with insurance type, external beam radiation therapy (EBRT) at an outside facility, and adenocarcinoma histology (p < 0.05). Time from diagnosis to completion of LACC staging was the interval most predictive of treatment delay (OR 3.7, CI 1.8-7.7). Treatment prolongation was associated with longer intervals between EBRT and brachytherapy (BT) (OR 2.6,CI 1.6-4.2) but not with time to initiate EBRT or EBRT duration. PFS and OS were not associated with primary outcomes. Conclusions: A quarter of patients waited over 2 months to initiate CRT, and half experienced prolonged treatment duration. Delays in staging and transitions in care, especially between institutions, contributed significantly to total patient delay.

Indexed as

Care delayCervical cancerChemoradiationHealth care accessLocally advanced cervical cancer

Identifiers

PMID41561675
PMCPMC12813220

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.