SynthesisFrontiers in neuroscience2025
Advances in glaucoma biomechanics from 2000 to 2024: a bibliometric study and visualization analysis.
Synthesis in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: Glaucoma is an irreversible progressive optic neuropathy characterized by neurodegeneration of retinal ganglion cells. Elevated intraocular pressure induces mechanical stress and strain at the optic nerve head, impairing axonal function and contributing to the onset and progression of glaucoma. This study aims to generalize and visualize the dynamic evolution and research hotspots of glaucoma biomechanics through bibliometric methods. Methods: All documents about glaucoma biomechanics research in 2000-2024 were extracted from two databases (Web of Science Core Collection and PubMed). The hotspots and frontiers of research in terms of remarkable countries, authors, journals, keywords, and cited references were analyzed using CiteSpace and VOSviewer programs. Results: A collection of 1,655 English articles was included, with a steady increase in annual publications. 4,464 authors from 51 countries/regions were identified, led by the United States. Ethier CR was the most prolific contributor, while Downs JC was the most commonly cited author. Among 203 journals, Conclusion: Our study employed bibliometric and visualization analyses to state the biomechanical mechanisms underlying intraocular pressure regulation and optic nerve damage, offering the development in the field of glaucoma biomechanics. Future directions may focus on the interdisciplinary applications of artificial intelligence, tissue engineering and novel biomaterials in glaucoma pathogenesis and therapies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.