ArticleACS catalysis2026
A Multi-Functional Heterogeneous Biocatalyst for the Oxygen-Free Oxidative Condensation of Primary Alcohols into β‑Hydroxy Acids.
Article in ACS catalysis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Enantiomerically pure β-hydroxy acids are valuable building blocks in polymer and fine chemical industries. However, biosynthetic routes to these compounds are limited by narrow feedstock availability. Here, we report a confined, cell-free biosynthetic pathway that converts primary alcohols into β-hydroxy acids using a multifunctional heterogeneous biocatalyst. Five enzymes were coimmobilized and spatially organized on glyoxyl-functionalized porous supports: an alcohol dehydrogenase from
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