Evidence map›Paper›PMID 41561350›Full record

ReviewFrontiers in bioengineering and biotechnology2025

Sensory feedback for gait in transtibial amputees: a narrative review of technologies and clinical outcomes.

Rita Suliman Hussain, Nasrul Anuar Abd Razak, Mahmoud Alfatafta, Chan Chow Khuen, Bashar Al Qaroot, Timothé Ramousse

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rita Suliman HussainDepartment of Biomedical Engineering, University Malaya, Kuala Lumpur, Malaysia.
Nasrul Anuar Abd RazakDepartment of Biomedical Engineering, University Malaya, Kuala Lumpur, Malaysia.
Mahmoud AlfataftaDepartment of Prosthetics and Orthotics, School of Rehabilitation Sciences, The University of Jordan, Amman, Jordan.
Chan Chow KhuenDepartment of Biomedical Engineering, University Malaya, Kuala Lumpur, Malaysia.
Bashar Al QarootDepartment of Prosthetics and Orthotics, School of Rehabilitation Sciences, The University of Jordan, Amman, Jordan.
Timothé RamousseDepartment of Biomedical Engineering, School of Polytech Marseille, Aix-Marseille University, Marseille, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The loss of somatosensory feedback in transtibial amputees contributes to gait asymmetry, increased metabolic cost, higher fall risk, and dependence on visual cues. Sensory neuroprostheses, both invasive and non-invasive, provide methods to restore aspects of this feedback and enhance functional mobility. This review combines recent findings from invasive procedures, such as intraneural electrodes, spinal cord stimulation, and agonist-antagonist myoneural constructs, with non-invasive electrotactile, mechanotactile, and vibrotactile techniques. Invasive systems offer high-quality somatotopic mapping that improves embodiment and reduces phantom limb pain but are limited by surgical risks, long-term stability issues, and scalability concerns. Non-invasive systems, especially those utilizing vibrotactile feedback, have demonstrated measurable benefits, including a 41% increase in walking speed, fewer stumbles, improved symmetry indices from approximately 60% to roughly 75%, and a 70% reduction in phantom limb pain in small clinical trials. However, most studies are limited by small sample sizes, short intervention durations, and laboratory-based testing, with inconsistent reporting of cognitive load, training doses, and real-world applicability. The analysis here highlights vibrotactile systems as the most practical near-term option for clinical use, while invasive approaches remain valuable for high-performance tasks requiring precise feedback. Future research should focus on larger, longer trials, standardized outcome reporting, and seamless integration of sensors and actuators into prosthetic sockets. Overcoming these challenges is key to developing scalable, next-generation sensory feedback systems capable of restoring natural and confident gait in transtibial amputees.

Indexed as

electrotactile stimulationgait symmetryrehabilitation engineeringsomatosensory feedbacktranstibial amputationvibrotactile stimulation

Identifiers

PMID41561350
PMCPMC12812926

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.