Evidence map›Paper›PMID 41561344›Full record

ArticleStructural heart : the journal of the Heart Team2026

Outcomes of Mitral Transcatheter Edge-to-Edge Repair in Patients With Small Mitral Valve Area.

Chloe Kharsa, Yasser M Sammour, Rasha Bazari, Alba Muñoz Estrella, Gal Sella, Sahar Samimi, Samarthkumar Thakkar, Mangesh Kritya, Taha Hatab, Rody G Bou Chaaya and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Structural heart : the journal of the Heart Team, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors.

Chloe KharsaCardiology Department, Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, USA.
Yasser M SammourCardiology Department, Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, USA.
Rasha BazariCardiology Department, Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, USA.
Alba Muñoz EstrellaCardiology Department, Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, USA.
Gal SellaCardiology Department, Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, USA.
Sahar SamimiCardiology Department, Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, USA.
Samarthkumar ThakkarCardiology Department, Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, USA.
Mangesh KrityaCardiology Department, Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, USA.
Taha HatabCardiology Department, Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, USA.
Rody G Bou ChaayaCardiology Department, Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, USA.
Syed ZaidCardiology Department, Michael E. DeBakey VA Medical Center, Houston, Texas, USA.
Joe AounCardiology Department, Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, USA.
Sherif F NaguehCardiology Department, Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, USA.
William A ZoghbiCardiology Department, Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, USA.
Marvin D AtkinsCardiology Department, Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, USA.
Michael ReardonCardiology Department, Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, USA.
Nadeen N FazaCardiology Department, Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, USA.
Stephen H LittleCardiology Department, Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, USA.
Gerald LawrieCardiology Department, Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, USA.
Neal S KleimanCardiology Department, Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, USA.
Sachin S GoelCardiology Department, Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: A small baseline mitral valve area (MVA) raises concern for iatrogenic mitral stenosis due to increased transmitral pressure gradients (TMPG) after mitral transcatheter edge-to-edge repair (M-TEER). Outcomes in patients with MVA <4.0 cm² remain limited, as this population has been largely excluded from clinical trials. Methods: We retrospectively analyzed 305 consecutive patients who underwent M-TEER (2014-2022). Patients were stratified by baseline MVA (<4.0 cm Results: Of 305 patients, 66 (21.6%) had MVA <4.0 cm². Women were more prevalent in the small MVA group (57.6% vs. 42.7%; p = 0.03). Patients with smaller MVA received fewer clips (1.3 ± 0.07 vs. 1.5 ± 0.04; Conclusions: M-TEER can be safely and effectively performed in patients with baseline MVA <4.0 cm

Indexed as

MitraClipMitral regurgitationMitral transcatheter edge-to-edge repairMitral valve areaPercutaneous mitral valve repair

Identifiers

PMID41561344
PMCPMC12813607

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.