SynthesisFrontiers in neurology2025
Acupuncture for nausea and vomiting induced by highly emetogenic chemotherapy: a systematic review and meta-analysis.
Synthesis in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficacy and safety of acupuncture for chemotherapy-induced nausea and vomiting: a systematic review and meta-analysis of randomized controlled trial.Frontiers in neurologyPooled it
- Patient-Controlled Real-Time Transcutaneous Electrical Acupoint Stimulation at Neiguan (PC6) for Chemotherapy-Induced Nausea and Vomiting in Breast Cancer: An Exploratory Single-Arm Two-Stage Trial.Current oncology (Toronto, Ont.) · 2026Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Acupuncture shows potential in treating nausea and vomiting (CINV) induced by highly emetogenic chemotherapy (HEC). However, the certainty of its efficacy evidence remains unclear, warranting a comprehensive evaluation. Method: Two independent reviewers systematically searched eight databases from inception to December 2024 to identify eligible randomized controlled trials (RCTs). Relevant data were extracted using a standardized form, and risk of bias was assessed using the Cochrane risk of bias tool version 2.0 (ROB 2.0). Meta-analysis was performed using R Studio 4.4 software. Subgroup analysis was conducted based on acupuncture type. Additionally, publication bias was detected using appropriate methods according to the heterogeneity of different outcomes, where appropriate. Finally, evidence quality was rated using the GRADE system. Result: A total of 58 RCTs were included in this meta-analysis. Rob 2.0 result indicated that most studies were at high risk of bias, with low methodological quality. For the primary outcome, acupuncture significantly improved the complete control rate during the overall (RR 1.54, 95% CI 1.36-1.75; Conclusion: Although acupuncture for HEC-induced CINV shows some positive effects, there are various limitations that render the current evidence insufficient to conclusively establish its efficacy; therefore, further high-quality studies are required. Systematic review registration: PROSPERO, identifier: CRD42024588165.
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Registered trials
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