ArticleCureus2025
Acute Carpopedal Spasm During Medical Termination of Pregnancy: A Case of Hyperventilation-Induced Hypocalcemia.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute neuromuscular symptoms during medical management of pregnancy loss are rare and may mimic life-threatening obstetric or neurologic emergencies. A 40-year-old multigravida woman at 14 weeks and 5 days of gestation was admitted for medical management of a missed abortion using sublingual misoprostol. Three hours after administration, she developed acute bilateral carpopedal spasms accompanied by hyperventilation, chest discomfort, agitation, and perioral numbness. Laboratory evaluation revealed marked respiratory alkalosis with reduced ionized calcium, while endocrine workup, including parathyroid hormone, vitamin D, and magnesium levels, was normal. Extensive assessment excluded uterine rupture, pulmonary embolism, sepsis, and seizure activity. Symptoms improved after intravenous calcium administration and resolved completely following expulsion of the gestational sac. This case highlights hyperventilation-induced respiratory alkalosis as a reversible cause of acute neuromuscular symptoms during medical management of pregnancy loss, underscoring the importance of prompt recognition, targeted treatment, and avoidance of unnecessary interventions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.