ArticleBiomedical reports2026
Integrated analysis of gut microbiota structure and metabolic function in patients with cirrhosis and refractory ascites.
Article in Biomedical reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- Beyond conventional treatments: cutting-edge strategies for ascites in cirrhosis.Frontiers in medicine · 2026Review
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Refractory ascites is a serious complication of decompensated cirrhosis, yet its intestinal microbial and metabolic characteristics remain incompletely understood. The present study combined 16S rRNA sequencing and gas chromatography-mass spectrometry-based untargeted metabolomics to investigate the gut microbial composition and metabolite profiles of 70 patients with refractory ascites due to cirrhosis (OB group) and 70 healthy individuals (NC group). Analyses included microbial diversity evaluation, taxonomic comparison, functional prediction, metabolite screening and disease association mapping. Compared with the NC group, the OB group showed reduced α diversity and distinct β diversity patterns, with enrichment of Proteobacteria and a reduction in anaerobic and Gram-positive taxa. BugBase analysis indicated increased proportions of potentially pathogenic, biofilm-forming and oxidative stress-tolerant phenotypes. LEfSe analysis further revealed group-specific taxa, such as enrichment of Bacteroidota and Actinobacteriota in the NC group and Firmicutes-related genera including
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