Evidence map›Paper›PMID 41561125›Full record

SynthesisFrontiers in cardiovascular medicine2025

Hypertriglyceridemic waist and subclinical atherosclerosis: a systematic review and meta-analysis.

Wei Xiong, Hua Fan, Yao You, Qingwen Yu, Ziyi Xin, Ting Tang, Xiyun Rao, Lanlan Feng, Yongmin Shi, Xuhan Tong and 5 more

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Wei Xiong *Department of Science and Education, The First People's Hospital of Jiande, Hangzhou, China.
Hua Fan *Office of Research and Innovation, The First Affiliated Hospital of Henan University of Science and Technology, Luoyang, China.
Yao You *Department of Cardiology, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China.
Qingwen YuDepartment of Cardiology, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China.
Ziyi XinDepartment of Cardiology, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China.
Ting TangDepartment of Cardiology, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China.
Xiyun RaoDepartment of Cardiology, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China.
Lanlan FengDepartment of Cardiology, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China.
Yongmin ShiDepartment of Cardiology, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China.
Xuhan TongDepartment of Cardiology, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China.
Jiake TangDepartment of Cardiology, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China.
Xinyan FuDepartment of Cardiology, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China.
Xingwei ZhangDepartment of Cardiology, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China.
Mingwei WangDepartment of Cardiology, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China.
Hangzhou LuoDepartment of Cardiology, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Atherosclerosis is a chronic, progressive inflammatory disease with a long asymptomatic period. Disease progression can eventually lead to acute cardiovascular events, such as myocardial infarction, unstable angina, and sudden cardiac death. Hypertriglyceridemic waist (HTGW) has received much attention recently as a cheap and non-invasive test. The purpose of our study was to explore whether the HTGW phenotype could be used as an effective test for subclinical atherosclerosis. Methods: We screened seven databases (PubMed, Cochrane Library, EMBASE, CNKI, WANFANG, CBM, and Web of Science) using both free terms and MeSH terms. Six published studies which evaluate the connection between HTGW and subclinical atherosclerosis were selected. Total carotid intima-media thickness (IMT) and carotid plaque are surrogate markers of subclinical atherosclerosis and predictors of cardiovascular events. Demographic and clinical data, data on HTGW and markers associated with subclinical atherosclerosis, along with odds ratios (OR), relative risks (RR), and hazard ratios (HR) with 95% confidence intervals were extracted. Data were then integrated using Stata 16. Results: A total of six studies conformed to inclusion criteria and revealed that HTGW is associated with subclinical atherosclerosis (OR = 2.39, 95% CI = 1.63-3.51). Conclusion: Available evidence supports the notion that HTGW can be an effective and inexpensive means of testing for atherosclerosis.

Indexed as

cardiovascular diseasecarotid intima-Media thicknesshypertriglyceridemic waistmeta-analysissubclinical atherosclerosis

Identifiers

PMID41561125
PMCPMC12812524

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.