Genomic insights into antibiotic resistance, virulence traits and phylogenetic lineages of 141 clinical

Pingping Wang, Jing Zhao, Bin Lv, Xiaohan Zhang, Ming Li, Shenglan Chen, Bingjie Fan, Wenhong Wang

Abstract read

In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Association of Resistance-AssociatedAntibiotics (Basel, Switzerland) · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pingping WangDepartment of Clinical Laboratory, Affiliated Taizhou Second People's Hospital of Yangzhou University, Taizhou, Jiangsu, China.

Jing ZhaoDepartment of Gastroenterology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.

Bin LvDepartment of Gastroenterology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.

Xiaohan ZhangCowin Medical Laboratory (Taizhou), Taizhou, Jiangsu, China.

Ming LiCowin Medical Laboratory (Taizhou), Taizhou, Jiangsu, China.

Shenglan ChenCowin Medical Laboratory (Taizhou), Taizhou, Jiangsu, China.

Bingjie FanDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China.

Wenhong WangDepartment of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To characterize antibiotic resistance, virulence genotypes and phylogenetic lineages of Methods: Whole-genome sequencing (WGS) and phenotypic antimicrobial susceptibility testing (AST) for 6 antibiotics were performed on 141 Results: Metronidazole resistance was highest (85.1%), followed by levofloxacin (57.4%), clarithromycin (53.9%) and amoxicillin (21.3%); tetracycline and furazolidone resistance was low at 2.8% and 0.7%, respectively. Key resistance mutations included Conclusion:

Indexed as

Drug Resistance, BacterialHelicobacter InfectionsHelicobacter pyloriPhylogenyVirulence FactorsAnti-Bacterial AgentsBacterial ProteinsChinaDNA GyraseGenome, BacterialGenotypeHumansMicrobial Sensitivity TestsMutationPhenotypeRNA, Ribosomal, 23SAnti-Bacterial AgentsBacterial ProteinsDNA GyraseRNA, Ribosomal, 23SVirulence Factorsantibiotic resistanceHelicobacter pyloriphylogenetic lineagesvirulence genotypeswhole-genome sequencing

Identifiers

PMID41561082

DOI10.3389/fcimb.2025.1726881

PMCPMC12812873

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.