ArticleFrontiers in endocrinology2025
Endometriosis burden and trends among women of childbearing age from 1990 to 2021.
Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Global, regional and national burden of colorectal cancer attributable to low-fiber diet from 1990 to 2021: a systematic analysis of the global burden of disease study 2021.Frontiers in nutrition · 2026Article
- Endometriosis-Associated Infertility in China: Epidemiological Trends, Future Projection, and Real-World Clinical Insights.International journal of women's health · 2026Article
- Temporal Trends and Future Projections of Oral Disorders Among Women of Childbearing Age in South Korea.International journal of women's health · 2026Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Endometriosis is a common disease among women of childbearing age (WCBA), significantly affecting their physiological health. This study systematically analyzes the global, regional, and national burden of endometriosis in WCBA based on the Global Burden of Disease 2021 (GBD 2021) database. Methods: This study focuses specifically on the WCBA population, evaluating the burden of endometriosis in terms of incidence, prevalence, mortality, and disability-adjusted life years (DALYs). Results: Globally, the number of prevalent cases of endometriosis among WCBA increased from 19.08 million in 1990 to 21.05 million in 2021, marking a 10% rise; incident cases grew from 3.326 million to 3.439 million, an increase of 3%; DALYs rose from 1.759 million to 1.939 million, a 10% increase; and deaths increased from 21.55 to 46.72, a rise of 117%. However, the age-standardized incidence, prevalence, and DALY rates showed downward trends, with EAPCs of -0.94, -1.12, and -0.93, respectively. Regions with a middle SDI level recorded the highest numbers of prevalent cases, incident cases, DALYs, and deaths. In 2021, endometriosis exhibited marked age-related differences worldwide. Women aged 25-29 had the highest number of prevalent cases and DALYs, those aged 20-24 had the highest incidence, and those aged 45-49 had the highest number of deaths. Conclusion: The global distribution of endometriosis varies significantly across regions, highlighting the need for public health policies to be tailored to regional contexts to optimize healthcare resource allocation.
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